Evidence map›Paper›PMID 33494262›Full record

ReviewInternational journal of molecular sciences2021

Genetic and Environmental Factors Influence the Pleomorphy of

Vinita G Chittoor-Vinod, R Jeremy Nichols, Birgitt Schüle

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Endoplasmic Reticulum Proteins Impact Penetrance in aInternational journal of molecular sciences · 2025
    Article
  3. Brain communications · 2025
    Article
  4. Review
  5. Article
  6. LRRK2-Associated Parkinsonism With and WithoutmedRxiv : the preprint server for health sciences · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. LRRK2 and Proteostasis in Parkinson's Disease.International journal of molecular sciences · 2022
    Review
  12. Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vinita G Chittoor-VinodDepartment Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0003-0518-8770
R Jeremy NicholsDepartment Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Birgitt SchüleDepartment Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-9952-5776
Stanford University · US

Funding

Stanford Alzheimer's Disease Research CenterAdmin Supp: Developing iPSC models for AD and PDP30AG066515 · NIA · STANFORD UNIVERSITY · PI ELIZABETH MORMINO · 2020 to 2026
$29.0M
Alexander and Eva Nemeth Foundation N/AFarmer Family Foundation Parkinson's Research Initiative N/AMichael J. Fox Foundation N/ANIA NIH HHS P30 AG066515NIH HHS P30AG066515-01Sergey Brin Family Foundation N/A
6 · The paper itself

Abstract

Missense mutations in the

Indexed as

Disease SusceptibilityEnvironmentGene-Environment InteractionPhenotypeAge FactorsAllelesAnimalsGenetic Predisposition to DiseaseHumansIncidenceLeucine-Rich Repeat Serine-Threonine Protein Kinase-2Multifactorial InheritanceMutationNeurodegenerative DiseasesParkinsonian DisordersPenetranceLeucine-Rich Repeat Serine-Threonine Protein Kinase-2environmental risk factorsgeneticsGWASLRRK2modifierneuropathologyparkinsonismParkinson’s diseasepolygenic risk score

Identifiers

PMID33494262
PMCPMC7864502
OpenAlexW3125032505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.