Evidence map›Paper›PMID 33494255›Full record

ArticleMolecules (Basel, Switzerland)2021

pH-Responsive Redox Nanoparticles Protect SH-SY5Y Cells at Lowered pH in a Cellular Model of Parkinson's Disease.

Monika Pichla, Grzegorz Bartosz, Ireneusz Stefaniuk, Izabela Sadowska-Bartosz

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Monika PichlaLaboratory of Analytical Biochemistry, Institute of Food Technology and Nutrition, College of Natural Sciences, Rzeszow University, 4 Zelwerowicza Street, 35-601 Rzeszow, Poland.ORCID 0000-0001-7469-260X
Grzegorz BartoszDepartment of Bioenergetics, Food Analysis and Microbiology, Institute of Food Technology and Nutrition, College of Natural Sciences, Rzeszow University, 4 Zelwerowicza Street, 35-601 Rzeszow, Poland.ORCID 0000-0002-0347-0740
Ireneusz StefaniukTeaching and Research Center of Microelectronics and Nanotechnology, College of Natural Sciences, University of Rzeszow, 35-959 Rzeszow, Poland.ORCID 0000-0003-2616-9595
Izabela Sadowska-BartoszLaboratory of Analytical Biochemistry, Institute of Food Technology and Nutrition, College of Natural Sciences, Rzeszow University, 4 Zelwerowicza Street, 35-601 Rzeszow, Poland.ORCID 0000-0001-9035-6833
University of Rzeszów · PL

Funding

Narodowe Centrum Nauki 2016/22/E/NZ7/00641
6 · The paper itself

Abstract

The damage to SH-SY5Y cells by 6-hydroxydopamine (6-OHDA) is an established cellular model of Parkinson's disease (PD). Redox nanoparticles are a promising tool for therapy, including neurodegenerative diseases. As pH of the brain tissue at sites affected by PD is lowered down to 6.5, we studied the effect of pH-responsive redox nanoparticles (poly(ethylene glycol)-

Indexed as

Models, NeurologicalNanoparticlesOxidopamineParkinson DiseaseCell Line, TumorCell SurvivalDelayed-Action PreparationsHumansHydrogen-Ion ConcentrationDelayed-Action PreparationsOxidopamine6-hydroxydopaminehuman neuroblastoma SH-SY5Y cellsParkinson’s diseasepH-responsive redox nanoparticles

Identifiers

PMID33494255
PMCPMC7864521
OpenAlexW3121932733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.