Evidence map›Paper›PMID 33494139›Full record

SynthesisInternational journal of environmental research and public health2021

Clinical Efficacy of Mesenchymal Stem Cells in Bone Regeneration in Oral Implantology. Systematic Review and Meta-Analysis.

Sonia Egido-Moreno, Joan Valls-Roca-Umbert, Juan Manuel Céspedes-Sánchez, José López-López, Eugenio Velasco-Ortega

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Posology and Serum-/Xeno-Free Engineered Adipose Stromal Cells Cell Sheets.Frontiers in cell and developmental biology · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sonia Egido-MorenoDepartment of Odontoestomatology, Faculty of Medicine and Health Sciences, School of Dentistry, University of Barcelona-Campus Bellvitge, 08907 Barcelona, Spain.
Joan Valls-Roca-UmbertDepartment of Odontoestomatology, Faculty of Medicine and Health Sciences, School of Dentistry, University of Barcelona-Campus Bellvitge, 08907 Barcelona, Spain.
Juan Manuel Céspedes-SánchezDepartment of Odontoestomatology, Faculty of Medicine and Health Sciences, School of Dentistry, University of Barcelona-Campus Bellvitge, 08907 Barcelona, Spain.
José López-LópezDepartment of Odontoestomatology, Faculty of Medicine and Health Sciences, School of Dentistry, University of Barcelona-Campus Bellvitge, 08907 Barcelona, Spain.ORCID 0000-0001-8035-4412
Eugenio Velasco-OrtegaDepartment of Stomatology, Faculty of Dentistry, University of Seville, 41013 Seville, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In bone regeneration, obtaining a vital bone as similar as possible to native bone is sought. This review aimed to evaluate the efficacy of stem cells in maxillary bone regeneration for implant rehabilitation and to review the different techniques for obtaining and processing these cells. A systematic review and meta-analysis were performed using the Pubmed/Medline (NCBI), Cochrane, Scielo, and Scopus databases, without restriction on the publication date. The following Mesh terms were used, combined by the Boolean operator "AND": "dental implants" AND "stem cells" AND "bioengineering". Applying inclusion and exclusion criteria, five articles were obtained and three were added after manual search. The results from the meta-analysis (18 patients) did not provide significant differences despite the percentage of bone formed in the maxillary sinus, favoring the stem cell group, and the analysis of the percentage of residual Bio-Oss

Indexed as

Mesenchymal Stem CellsBone RegenerationBone TransplantationHumansMaxillary SinusTreatment Outcomebioengineeringdental implantsregenerationstem cells

Identifiers

PMID33494139
PMCPMC7908266

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.