Evidence map›Paper›PMID 33493639›Full record

ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2021

Asthma and allergic diseases are not risk factors for hospitalization in children with coronavirus disease 2019.

Burcin Beken, Gokcen Kartal Ozturk, Fatma Deniz Aygun, Cigdem Aydogmus, Himmet Haluk Akar

Open access · bronzeAbstract read
In one paragraph

Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. The impact of comorbid allergic airway disease on the severity and mortality of COVID-19: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Pooled it
  3. Pooled it
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  6. Altered COVID-19 immunity in children with asthma by atopic status.The journal of allergy and clinical immunology. Global · 2024
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  16. Allergic diseases and immunodeficiencies in children, lessons learnt from COVID-19 pandemic by 2022: A statement from the EAACI-section on pediatrics.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
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  18. COVID-19 Infections and Asthma.The journal of allergy and clinical immunology. In practice · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Burcin BekenDepartment of Pediatric Allergy and Immunology, Kanuni Sultan Suleyman Training, and Research Hospital, Istanbul, Turkey. Electronic address: burcinbeken@gmail.com.
Gokcen Kartal OzturkDepartment of Pediatric Pulmonology, Kanuni Sultan Suleyman Training, and Research Hospital, Istanbul, Turkey.
Fatma Deniz AygunDepartment of Pediatric Infectious Diseases, Kanuni Sultan Suleyman Training, and Research Hospital, Istanbul, Turkey.
Cigdem AydogmusDepartment of Pediatric Allergy and Immunology, Kanuni Sultan Suleyman Training, and Research Hospital, Istanbul, Turkey.
Himmet Haluk AkarDepartment of Pediatric Allergy and Immunology, Kanuni Sultan Suleyman Training, and Research Hospital, Istanbul, Turkey.
İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) emerged as a pandemic toward the end of 2019, causing large numbers of people to become infected and die.

objectiveTo determine whether allergic diseases are a risk factor for hospitalization in COVID-19.

methodsWe conducted a study including 107 pediatric patients after COVID-19 recovery. The International Study of Asthma and Allergies in Childhood Phase 3 questionnaires were distributed together with a detailed history of environmental factors and an allergic evaluation including skin prick tests, specific immunoglobulin E tests, and spirometry. We investigated the prevalence of allergic diseases and evaluated the factors associated with hospitalization in COVID-19.

resultsA total of 61 (57%) patients were hospitalized and 46 (43%) patients were followed closely in the outpatient clinic. The prevalences of allergic rhinitis, asthma, atopic dermatitis, and episodic wheezing were 10.3%, 6,5%, 4.7%, and 3.7%, respectively, within the whole study population. Although having asthma with or without allergic rhinitis, atopic dermatitis, and passive tobacco exposure were not found to be related to hospitalization because of COVID-19, having a pet at home was found to decrease the risk of hospitalization (odds ratio, 0.191; 95% confidence interval, 0.047-0.779; P = .02). Spirometry tests revealed a higher forced expiratory volume in one second to forced vital capacity ratio and a peak expiratory flow reversibility in hospitalized patients than in nonhospitalized ones (P = .02 and P = .003, respectively).

conclusionAsthma and allergic diseases do not seem to be risk factors for hospitalization in children because of COVID-19, and having a pet at home can be a protective effect. Pulmonary function testing seems to be important for monitoring lung damage after COVID-19.

Indexed as

AdolescentAsthmaChildChild, PreschoolCoinfectionCOVID-19Dermatitis, AtopicDisease SusceptibilityFemaleForced Expiratory VolumeHospitalizationHumansInfantMaleProspective StudiesRhinitis, AllergicTobacco Smoke Pollution

Identifiers

PMID33493639
PMCPMC7825986
OpenAlexW3124723903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.