Evidence map›Paper›PMID 33493532›Full record

Observational studyThe Journal of investigative dermatology2021

FLG Variation Differs between European Americans and African Americans.

Yaqian Zhu, Nandita Mitra, Yuanqing Feng, Sarah Tishkoff, Ole Hoffstad, David Margolis

Abstract readLetterObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The Journal of investigative dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Relevance of Coding Variation inJID innovations : skin science from molecules to population health · 2023
    Article
  2. Review
  3. Structural racism and its pathways to asthma and atopic dermatitis.The Journal of allergy and clinical immunology · 2021
    Review
  4. Immune and barrier characterization of atopic dermatitis skin phenotype in Tanzanian patients.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021
    Article
  5. Cracking the Skin Barrier: Liquid-Liquid Phase Separation Shines under the Skin.JID innovations : skin science from molecules to population health · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yaqian ZhuDepartment of Biostatistics, Epidemiology & Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address: yazhu@pennmedicine.upenn.edu.
Nandita MitraDepartment of Biostatistics, Epidemiology & Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yuanqing FengDepartments of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sarah TishkoffDepartments of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Biology, School of Arts & Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ole HoffstadDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
David MargolisDepartment of Biostatistics, Epidemiology & Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Funding

Genetic and molecular basis for variation in human skin pigmentationR01AR076241 · NIAMS · CHILDREN'S HOSP OF PHILADELPHIA · PI MARKS, MICHAEL S, OANCEA, ELENA · 2020 to 2024
$5.5M
Integrative Genomic Analyses of Human Evolution and Adaptation in AfricaR35GM134957 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI TISHKOFF, SARAH ANNE · 2020 to 2024
$2.7M
African-Americans with Atopic Dermatitis: Skin Barrier and ImmuneR01AR069062 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MARGOLIS, DAVID · 2016 to 2021
$2.4M
NIAMS NIH HHS R01 AR069062NIAMS NIH HHS R01 AR076241NIGMS NIH HHS R35 GM134957
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Black or African AmericanChildDermatitis, AtopicFilaggrin ProteinsHumansPolymorphism, Single NucleotideProspective StudiesS100 ProteinsWhite PeopleFilaggrin ProteinsFLG protein, humanS100 Proteins

Identifiers

PMID33493532
PMCPMC8238796

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.