Evidence map›Paper›PMID 33493432›Full record

ArticleJournal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons2021

A Better Understanding of Unilateral Condylar Hyperplasia of the Mandible.

Jaime Gateno, Kevin B Coppelson, Tianshu Kuang, Cathy D Poliak, James J Xia

Abstract read
In one paragraph

Article in Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Observational
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jaime GatenoChairman, Oral and Maxillofacial Surgery Department, Houston Methodist Hospital, Houston, TX; Professor of Oral and Maxillofacial Surgery, Houston Methodist Academic Institute, Houston, TX; and Professor of Clinical Surgery (Oral and Maxillofacial), Weill-Cornell Medical College, New York, NY.
Kevin B CoppelsonFormer Advance Oral and Maxillofacial Surgery Fellow, Department of Oral and Maxillofacial Surgery, Houston Methodist Hospital, Houston, TX.
Tianshu KuangResearch Assistant, Surgical Planning Laboratory, Houston Methodist Hospital, Houston, TX.
Cathy D PoliakConoco-Phillips Instructional Assistant Professor of Data Science, Associate Director MSDS Program, Mathematics Department, University of Houston, Houston, TX.
James J XiaDirector of the Surgical Planning Laboratory, Oral and Maxillofacial Surgery Department, Houston Methodist Research Institute; Professor of Oral and Maxillofacial Surgery, Houston Methodist Academic Institute, Houston, TX; and Professor of Surgery (Oral and Maxillofacial Surgery), Weill-Cornell Medical College, New York, NY. Electronic address: JXia@HoustonMethodist.org.

Funding

Outcome-Driven Approach to Minimize the Risks of Facial Distortion Following CMF SurgeryR01DE021863 · NIDCR · METHODIST HOSPITAL RESEARCH INSTITUTE · PI GATENO, JAIME · 2013 to 2025
$5.1M
A Novel Imaging Informatics Platform for Craniomaxillofacial SurgeryR01DE022676 · NIDCR · METHODIST HOSPITAL RESEARCH INSTITUTE · PI GATENO, JAIME · 2011 to 2020
$4.0M
Learning-Based Approach for Personalized Craniomaxillofacial Surgical PlanningR01DE027251 · NIDCR · METHODIST HOSPITAL RESEARCH INSTITUTE · PI GATENO, JAIME · 2017 to 2021
$2.9M
NIDCR NIH HHS R01 DE021863NIDCR NIH HHS R01 DE022676NIDCR NIH HHS R01 DE027251
6 · The paper itself

Abstract

purposeOur current understanding of unilateral condylar hyperplasia (UCH) was put forth by Obwegeser. He hypothesized that UCH is 2 separate conditions: hemimandibular hyperplasia and hemimandibular elongation. This hypothesis was based on the following 3 assumptions: 1) the direction of overgrowth, in UCH, is bimodal-vertical or horizontal, with rare cases growing obliquely; 2) UCH can expand a hemimandible with and without significant condylar enlargement; and 3) there is an association between the condylar expansion and the direction of overgrowth-minimal expansion resulting in horizontal growth and significant enlargement causing vertical displacement. The purpose of this study was to test these assumptions. PATIENTS AND

methodsWe analyzed the computed tomography scans of 40 patients with UCH. First, we used a Silverman Cluster analysis to determine how the direction of overgrowth is distributed in the UCH population. Next, we evaluated the relationship between hemimandibular overgrowth and condylar enlargement to confirm that overgrowth can occur independently of condylar expansion. Finally, we assessed the relationship between the degree of condylar enlargement and the direction of overgrowth to ascertain if condylar expansion determines the direction of growth.

resultsOur first investigation demonstrates that the general impression that UCH is bimodal is wrong. The growth vectors in UCH are unimodally distributed, with the vast majority of cases growing diagonally. Our second investigation confirms the observation that UCH can expand a hemimandible with and without significant condylar enlargement. Our last investigation determined that in UCH, there is no association between the degree of condylar expansion and the direction of the overgrowth.

conclusionsThe results of this study disprove the idea that UCH is 2 different conditions: hemimandibular hyperplasia and hemimandibular elongation. It also provides new insights about the pathophysiology of UCH.

Indexed as

Facial AsymmetryMandibular CondyleHumansHyperplasiaHypertrophyMaleMandible

Identifiers

PMID33493432
PMCPMC8096674

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.