Evidence map›Paper›PMID 33493283›Full record

ArticleJournal of biomechanical engineering2021

Design of a Single Layer Metamaterial for Pressure Offloading of Transtibial Amputees.

Nathan Brown, Meredith K Owen, Anthony Garland, John D DesJardins, Georges M Fadel

Open access · greenAbstract read
In one paragraph

Article in Journal of biomechanical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Assessment of 3D printed mechanical metamaterials for prosthetic liners.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nathan BrownDepartment of Mechanical Engineering, Clemson University, 218 South Palmetto Building, Clemson, SC 29631.
Meredith K OwenDepartment of Bioengineering, Clemson University, 118 Engineering Service Drive, Clemson, SC 29634.
Anthony GarlandCenter for Integrated Nanotechnologies, Sandia National Laboratories, 1515 Eubank Building SE, Albuquerque, NM 87123.
John D DesJardinsDepartment of Bioengineering, Clemson University, 118 Engineering Service Drive, Clemson, SC 29634.
Georges M FadelDepartment of Mechanical Engineering, Clemson University, 218 South Palmetto Building, Clemson, SC 29631.
Clemson University · USSandia National Laboratories · US

Funding

Tissue Structural and Neural Remodeling in Human Sacroiliac JointP20GM121342 · NIGMS · CLEMSON UNIVERSITY · PI Hai Yao · 2018 to 2026
$24.7M
NIGMS NIH HHS P20 GM121342
6 · The paper itself

Abstract

While using a prosthesis, transtibial amputees can experience pain and discomfort brought on by large pressure gradients at the interface between the residual limb and the prosthetic socket. Current prosthetic interface solutions attempt to alleviate these pressure gradients using soft homogenous liners to reduce and distribute pressures. This research investigates an additively manufactured metamaterial inlay with a tailored mechanical response to reduce peak pressure gradients around the limb. The inlay uses a hyperelastic behaving metamaterial (US10244818) comprised of triangular pattern unit cells, 3D printed with walls of various thicknesses controlled by draft angles. The hyperelastic material properties are modeled using a Yeoh third-order model. The third-order coefficients can be adjusted and optimized, which corresponds to a change in the unit cell wall thickness to create an inlay that can meet the unique offloading needs of an amputee. Finite element analysis simulations evaluated the pressure gradient reduction from (1) a standard homogenous silicone liner, (2) a prosthetist's inlay prescription that utilizes three variations of the metamaterial, and (3) a metamaterial solution with optimized Yeoh third-order coefficients. Compared to a traditional homogenous silicone liner for two unique limb loading scenarios, the prosthetist prescribed inlay and the optimized material inlay can achieve equal or greater pressure gradient reduction capabilities. These preliminary results show the potential feasibility of implementing this metamaterial as a method of personalized medicine for transtibial amputees by creating a customizable interface solution to meet the unique performance needs of an individual patient.

Indexed as

AmputeesPressureProsthesis DesignTibiaArtificial LimbsFinite Element AnalysisHumansPrinting, Three-Dimensional

Identifiers

PMID33493283
PMCPMC10782866
OpenAlexW3031442891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.