ArticlePLoS neglected tropical diseases2021
Malaria in Southern Venezuela: The hottest hotspot in Latin America.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Resurgence of Malaria in Protected and Rural Areas After Successful Control Program in a Brazilian Amazon Municipality.GeoHealth · 2026Article
- Political stability, health system resilience, and macroeconomic shocks as factors associated with malaria control outcomes: a comparative analysis of Ecuador and Venezuela (2000-2023).Malaria journal · 2026Article
- Highly sensitive detection of species-specific malaria antigens using a cellulose nanobead-based lateral flow immunoassay.Mikrochimica acta · 2026Article
- Territorial Persistence of ResidualTropical medicine and infectious disease · 2026Article
- Review
- PvGTSeq and PvCRiSP: Two amplicon-based targeted sequencing panels for Plasmodium vivax.PLoS neglected tropical diseases · 2026Article
- Population genomics ofScience (New York, N.Y.) · 2026Article
- MMS Américas: a regional network for malaria molecular surveillance.Malaria journal · 2026Article
- What impact did the Brazilian Federal Government's intervention have on malaria cases in the Yanomami Indigenous lands?Malaria journal · 2025Article
- Real-time malaria detection in the Amazon rainforest via drone-collected eDNA and portable qPCR.One health (Amsterdam, Netherlands) · 2025Article
- Article
- First detection of Nyssorhynchus rondoniensis (Diptera: Culicidae) in southern Venezuela and its infection with Plasmodium falciparum.Acta tropica · 2025Article
- A Pan-Amazonian dataset integrating 20 years of respiratory, cardiovascular, zoonotic and vector-borne disease cases and landscape changes.Scientific data · 2025Article
- TLR9 gene polymorphism -1237T/C (rs5743836) is associated with low IgG antibody response against PvCSP variants in symptomatic P. vivax infections in Venezuela.PLoS neglected tropical diseases · 2025Article
- Human migrations, anthropogenic changes, and insect-borne diseases in Latin America.Parasites & vectors · 2025Review
- Detection of endosymbiotic, environmental, and potential bacterial pathogens in diverse mosquito taxa from Colombian tropical forests using RNAseq.Frontiers in microbiology · 2025Article
- CUREMA project: a further step towards malaria elimination among hard-to-reach and mobile populations.Malaria journal · 2024Article
- Leveraging limited data from wildlife monitoring in a conflict affected region in Venezuela.Scientific reports · 2024Article
- A snapshot of a representative Brazilian state of illegal mining in indigenous areas during the era of malaria elimination.Cadernos de saude publica · 2024Article
- What's needed to sustain malaria elimination in the Region of the Americas.Bulletin of the World Health Organization · 2023Article
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Authors and funding
11 authors.
Funding
Abstract
Malaria elimination in Latin America is becoming an elusive goal. Malaria cases reached a historical ~1 million in 2017 and 2018, with Venezuela contributing 53% and 51% of those cases, respectively. Historically, malaria incidence in southern Venezuela has accounted for most of the country's total number of cases. The efficient deployment of disease prevention measures and prediction of disease spread to new regions requires an in-depth understanding of spatial heterogeneity on malaria transmission dynamics. Herein, we characterized the spatial epidemiology of malaria in southern Venezuela from 2007 through 2017 and described the extent to which malaria distribution has changed country-wide over the recent years. We found that disease transmission was focal and more prevalent in the southeast region of southern Venezuela where two persistent hotspots of Plasmodium vivax (76%) and P. falciparum (18%) accounted for ~60% of the total number of cases. Such hotspots are linked to deforestation as a consequence of illegal gold mining activities. Incidence has increased nearly tenfold over the last decade, showing an explosive epidemic growth due to a significant lack of disease control programs. Our findings highlight the importance of spatially oriented interventions to contain the ongoing malaria epidemic in Venezuela. This work also provides baseline epidemiological data to assess cross-border malaria dynamics and advocates for innovative control efforts in the Latin American region.
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