ArticleStroke2021
Sex, Age, and Socioeconomic Differences in Nonfatal Stroke Incidence and Subsequent Major Adverse Outcomes.
Article in Stroke, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Shunting for idiopathic normal pressure hydrocephalus.The Cochrane database of systematic reviews · 2024Pooled it
- Pooled it
- Cardiovascular Outcomes in a SELECT-Like Obesity Cohort: Real-World Insights From the Swedish AROS Database.Diabetes, obesity & metabolism · 2026Article
- Sex-Specific Association Between Socioeconomic Status and Stroke Mortality.Journal of the American Heart Association · 2026Article
- Trends in the Association of Neighborhood Socioeconomic Status With Stroke Incidence and Mortality From 2000 to 2022: A Population-Based Study.Journal of the American Heart Association · 2026Article
- Bidirectional brain-heart interactions in health and disease.Nature reviews. Neurology · 2026Review
- Trends in Antithrombotic Therapy Initiation Among Patients With Stroke Pre- and Post-COVID-19 in Sweden-An Interrupted Time Series Study.Basic & clinical pharmacology & toxicology · 2026Article
- The influence of upper extremity improvement on daily function in individuals with chronic stroke following task-oriented interventions: a structural equation modeling approach.Journal of neuroengineering and rehabilitation · 2026Article
- Stroke Action Plan for Europe 2018-2030 (SAP-E): mid-term review and update.European stroke journal · 2026Review
- Clinical implications of the recalibrated CHA₂DS₂-VA score for women after ischemic stroke: a prospective cohort study.Acta neurologica Belgica · 2025Observational
- Area-Level Income Disparities and the Timing of First Ischemic Stroke: Insights From the 2019 National Inpatient Sample.Journal of the American Heart Association · 2025Article
- Infantile Subacute Brainstem Infarction and the Presence of Incidental Ectopic Lymphoid Tissue: A Rare Case.Cureus · 2025Article
- Article
- Interplay of Acquired Risk Factors, Age, and Genetic Predisposition in Incident Stroke: A Prospective Cohort Study.Journal of the American Heart Association · 2025Article
- Article
- Socioeconomic Status and Stroke: A Review of the Latest Evidence on Inequalities and Their Drivers.Stroke · 2025Review
- Modifiable Risk Factors for Stroke in Syria: A Nationwide Multi-centre Case-Control Study.Scientific reports · 2025Article
- Mind the Gaps: Literature Survey Reveals Shortcomings in Handling Missing Data in Clinical Practice Research Datalink (CPRD), a UK Primary Care Health Records Database.Clinical epidemiology · 2025Article
- Cost-utility analysis of Coronary Artery Calcium screening to guide statin prescription among intermediate-risk patients in Thailand.PloS one · 2025Article
- Standardizing Domains and Metrics of Stroke Recovery: A Systematic Review.Brain sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
background and purposeData about variations in stroke incidence and subsequent major adverse outcomes are essential to inform secondary prevention and prioritizing resources to those at the greatest risk of major adverse end points. We aimed to describe the age, sex, and socioeconomic differences in the rates of first nonfatal stroke and subsequent major adverse outcomes.
methodsThe cohort study used linked Clinical Practice Research Datalink and Hospital Episode Statistics data from the United Kingdom. The incidence rate (IR) ratio of first nonfatal stroke and subsequent major adverse outcomes (composite major adverse cardiovascular events, recurrent stroke, cardiovascular disease-related, and all-cause mortality) were calculated and presented by year, sex, age group, and socioeconomic status based on an individual's location of residence, in adults with incident nonfatal stroke diagnosis between 1998 and 2017.
resultsA total of 82 774 first nonfatal stroke events were recorded in either primary care or hospital data-an IR of 109.20 per 100 000 person-years (95% CI, 108.46-109.95). Incidence was significantly higher in women compared with men (IR ratio, 1.13 [95% CI, 1.12-1.15];
conclusionsIn the United Kingdom, incidence of initial stroke and subsequent major adverse outcomes are higher in women, older populations, and people living in socially deprived areas.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.