Evidence map›Paper›PMID 33492994›Full record

ArticleJCO clinical cancer informatics2021

Feasibility of Fitness Tracker Usage to Assess Activity Level and Toxicities in Patients With Colorectal Cancer.

William H Ward, Caitlin R Meeker, Elizabeth Handorf, Maureen V Hill, Margret Einarson, R Katherine Alpaugh, Thomas L Holden, Igor Astsaturov, Crystal S Denlinger, Michael J Hall and 7 more

Registry-linked trialAbstract read
In one paragraph

Article in JCO clinical cancer informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07084181 (Get Your Rear In Gear Study), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07084181 completednot on this map

Get Your Rear In Gear Study: Feasibility of Using Fitness Tracker to Assess Activity Level and Toxicities in Patients With Localized/Advanced Colorectal Cancer: A Fox Chase Cancer Center Pilot Study

TypeobservationalSponsorFox Chase Cancer CenterRan2017 to 2019Enrolled80ConditionsColorectal Cancer (Diagnosis)
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

William H WardDepartment of Surgery, Naval Medical Center, Portsmouth, VA.
Caitlin R MeekerCancer Prevention and Control, Fox Chase Cancer Center, Philadelphia, PA.
Elizabeth HandorfBiostatistics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA.
Maureen V HillDepartment of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Margret EinarsonHigh Throughput Screening, Fox Chase Cancer Center, Philadelphia, PA.
R Katherine AlpaughProtocol Support Laboratory, Fox Chase Cancer Center, Philadelphia, PA.
Thomas L HoldenDepartment of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Igor AstsaturovDepartment of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Crystal S DenlingerDepartment of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Michael J HallDepartment of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Sanjay S ReddyDepartment of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Elin R SigurdsonDepartment of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Efrat DotanDepartment of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Matthew ZibelmanDepartment of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Joshua E MeyerDepartment of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Jeffrey M FarmaDepartment of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA.
Namrata VijayvergiaDepartment of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA.

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Margaret von Mehren · 1985 to 2026
$138.8M
Margret B. Einarson, Ph.D., Manager, High Throughput Screening Facility, Fox Chase Cancer CenterR50CA211479 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI EINARSON, MARGRET B · 2017 to 2021
$636k
Multiplexing biomarker analyzerS10OD021754 · OD · RESEARCH INST OF FOX CHASE CAN CTR · PI GOLEMIS, ERICA A. · 2016 to 2016
$76k
NCI NIH HHS P30 CA006927NCI NIH HHS R50 CA211479NIH HHS S10 OD021754
6 · The paper itself

Abstract

purposePerformance status (PS) is a subjective assessment of patients' overall health. Quantification of physical activity using a wearable tracker (Fitbit Charge [FC]) may provide an objective measure of patient's overall PS and treatment tolerance. MATERIALS AND

methodsPatients with colorectal cancer were prospectively enrolled into two cohorts (medical and surgical) and asked to wear FC for 4 days at baseline (start of new chemotherapy [± 4 weeks] or prior to curative resection) and follow-up (4 weeks [± 2 weeks] after initial assessment in medical and postoperative discharge in surgical cohort). Primary end point was feasibility, defined as 75% of patients wearing FC for at least 12 hours/d, 3 of 4 assigned days. Mean steps per day (SPD) were correlated with toxicities of interest (postoperative complication or ≥ grade 3 toxicity). A cutoff of 5,000 SPD was selected to compare outcomes.

resultsEighty patients were accrued over 3 years with 55% males and a median age of 59.5 years. Feasibility end point was met with 68 patients (85%) wearing FC more than predefined duration and majority (91%) finding its use acceptable. The mean SPD count for patients with PS 0 was 6,313, and for those with PS 1, it was 2,925 (122 and 54 active minutes, respectively) (

conclusionAssessment of physical activity with FC is feasible in patients with colorectal cancer and well-accepted. SPD may serve as an adjunct to PS assessment and a possible tool to help predict toxicities, regardless of type of therapy. Future studies incorporating FC can standardize patient assessment and help identify vulnerable population.

Indexed as

Colorectal NeoplasmsFitness TrackersExerciseFeasibility StudiesFemaleHumansMaleMiddle AgedPostoperative Complications

Identifiers

PMID33492994
PMCPMC8189607

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.