Evidence map›Paper›PMID 33492949›Full record

ArticleAnalytical chemistry2021

Trapped Ion Mobility Spectrometry of Native Macromolecular Assemblies.

Kevin Jeanne Dit Fouque, Alyssa Garabedian, Fenfei Leng, Yuk-Ching Tse-Dinh, Mark E Ridgeway, Melvin A Park, Francisco Fernandez-Lima

Abstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Collision-Induced Unfolding of High-Journal of the American Society for Mass Spectrometry · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Evaluation of a Commercial TIMS-Q-TOF Platform for Native Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Enhancing the Depth of Analyses with Next-Generation Ion Mobility Experiments.Annual review of analytical chemistry (Palo Alto, Calif.) · 2023
    Review
  16. Distinct mechanism of TbPhysical chemistry chemical physics : PCCP · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kevin Jeanne Dit FouqueDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, United States.
Alyssa GarabedianDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, United States.
Fenfei LengDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, United States.ORCID 0000-0002-9024-1216
Yuk-Ching Tse-DinhDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, United States.
Mark E RidgewayBruker Daltonics Inc., Billerica, Massachusetts 01821, United States.
Melvin A ParkBruker Daltonics Inc., Billerica, Massachusetts 01821, United States.
Francisco Fernandez-LimaDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, United States.ORCID 0000-0002-1283-4390

Funding

Supplement for undergraduate research participant to promote diversityR01GM054226 · NIGMS · NEW YORK MEDICAL COLLEGE · PI TSE-DINH, YUK-CHING · 1996 to 2020
$4.6M
Development of Multidimensional, Linear and Differential Ion Mobility MS Separations for Middle-Down ProteoformsR01GM134247 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI FERNANDEZ-LIMA, FRANCISCO · 2019 to 2022
$1.7M
Structure, Mechanism and Interactions of Type IA TopoisomerasesR35GM139817 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI TSE-DINH, YUK-CHING · 2021 to 2025
$1.6M
Targeting transcription-coupled DNA supercoiling for discovering antibiotics against bacterial DNA gyraseR21AI125973 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI LENG, FENFEI · 2017 to 2018
$478k
NIAID NIH HHS R21 AI125973NIGMS NIH HHS R01 GM054226NIGMS NIH HHS R01 GM134247NIGMS NIH HHS R35 GM139817
6 · The paper itself

Abstract

The structural elucidation of native macromolecular assemblies has been a subject of considerable interest in native mass spectrometry (MS), and more recently in tandem with ion mobility spectrometry (IMS-MS), for a better understanding of their biochemical and biophysical functions. In the present work, we describe a new generation trapped ion mobility spectrometer (TIMS), with extended mobility range (

Indexed as

Ion Mobility SpectrometryProteinsIonsMass SpectrometryUbiquitinIonsProteinsUbiquitin

Identifiers

PMID33492949
PMCPMC8327357

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.