Evidence map›Paper›PMID 33492934›Full record

ArticleBioconjugate chemistry2021

Copper-Free Click Enabled Triazabutadiene for Bioorthogonal Protein Functionalization.

Anjalee N Wijetunge, Garrett J Davis, Mehrdad Shadmehr, Julia A Townsend, Michael T Marty, John C Jewett

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anjalee N WijetungeDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Garrett J DavisDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Mehrdad ShadmehrDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Julia A TownsendDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Michael T MartyDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0000-0001-8115-1772
John C JewettDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0000-0001-5822-4080
University of Arizona · US

Funding

CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAMT32GM008804 · NIGMS · UNIVERSITY OF ARIZONA · PI MONTFORT, WILLIAM R. · 2003 to 2023
$3.9M
Unravelling Membrane Protein-Lipid Interactions using Nanodiscs and Mass SpectrometryR35GM128624 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Michael T Marty · 2018 to 2026
$3.6M
NIGMS NIH HHS R35 GM128624NIGMS NIH HHS T32 GM008804
6 · The paper itself

Abstract

Aryl diazonium ions have long been used in bioconjugation due to their reactivity toward electron-rich aryl residues, such as tyrosine. However, their utility in biological systems has been restricted due to the requirement of harsh conditions for their generation

Indexed as

Click ChemistryButadienesCopperElectrophoresis, Polyacrylamide GelProteinsButadienesCopperProteins

Identifiers

PMID33492934
PMCPMC7895501
OpenAlexW3121815395

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.