Evidence map›Paper›PMID 33492774›Full record

Trial reportCancer medicine2021

R-COMP versus R-CHOP as first-line therapy for diffuse large B-cell lymphoma in patients ≥60 years: Results of a randomized phase 2 study from the Spanish GELTAMO group.

Juan-Manuel Sancho, Rubén Fernández-Alvarez, Francisco Gual-Capllonch, Esther González-García, Carlos Grande, Norma Gutiérrez, María-Jesús Peñarrubia, Ana Batlle-López, Eva González-Barca, José-María Guinea and 9 more

Open access · goldAbstract readClinical Trial, Phase IIComparative StudyMulticenter Study
In one paragraph

Trial report in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 1 country.

Juan-Manuel SanchoHematology Department, ICO-IJC-Hospital Germans Trias i Pujol, Badalona, Spain.ORCID 0000-0001-7168-6538
Rubén Fernández-AlvarezHematology Department, Hospital de Cabueñes, Gijón, Spain.
Francisco Gual-CapllonchCardiology Department of Hospital Germans Trias i Pujol, Badalona, Spain.
Esther González-GarcíaHematology Department, Hospital de Cabueñes, Gijón, Spain.
Carlos GrandeHematology Department, Hospital Doce de Octubre, Madrid, Spain.
Norma GutiérrezHematology Department, Hospital Universitario de Salamanca, IBSAL, CIBERONC, Salamanca, Spain.
María-Jesús PeñarrubiaHematology Department, Hospital Clínico de Valladolid, Valladolid, Spain.
Ana Batlle-LópezHematology Department, Hospital Marqués de Valdecilla, Santander, Spain.
Eva González-BarcaHematology Department, ICO-Hospital Durán i Reynals (Hospitalet de Llobregat, Barcelona, Spain.ORCID 0000-0002-1323-1508
José-María GuineaHematology Department, Hospital Universitario de Araba, Vitoria, Spain.
Eva GimenoHematology Department, Hospital del Mar, Barcelona, Spain.
Francisco-Javier PeñalverHematology Department, Hospital Universitario Fundación de Alcorcón, Madrid, Spain.
Miguel FuertesHematology Department, Hospital Clínico Lozano Blesa, Zaragoza, Spain.
Mariana BastosHematology Department, Hospital Gregorio Marañón, Madrid, Spain.ORCID 0000-0002-9431-4646
José-Ángel Hernández-RivasHematology Department, Hospital Universitario Infanta Leonor, Madrid, Spain.
José-María MoraledaHematology Department, Hospital Virgen de la Arrixaca, Murcia, Spain.
Olga GarcíaHematology Department, ICO-IJC-Hospital Germans Trias i Pujol, Badalona, Spain.
Marc SoriguéHematology Department, ICO-IJC-Hospital Germans Trias i Pujol, Badalona, Spain.
Alejandro MartinHematology Department, Hospital Universitario de Salamanca, IBSAL, CIBERONC, Salamanca, Spain.
Hospital Universitari Germans Trias i Pujol · ESHospital Universitario De Cabueñes · ESInstituto de Investigación Biomédica de Salamanca · ESDuran i Reynals Hospital · ESHospital Clínico Universitario de Valladolid · ESHospital Clínico Universitario Lozano Blesa · ESHospital Del Mar · ESHospital General Universitario Gregorio Marañón · ESHospital Universitario 12 De Octubre · ESHospital Universitario Araba · ESHospital Universitario Fundación Alcorcón · ESHospital Universitario Infanta Leonor · ESHospital Universitario Virgen de la Arrixaca · ESMarqués de Valdecilla University Hospital · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of non-pegylated liposomal doxorubicin (Myocet

Indexed as

AgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDoxorubicinFemaleHumansLymphoma, Large B-Cell, DiffuseMaleMiddle AgedPrednisoneProspective StudiesRetrospective StudiesRituximabTreatment OutcomeVentricular Function, LeftCyclophosphamideDoxorubicinPrednisoneR-CHOP protocolRituximabVincristinecardiotoxicitydiffuse large B-cell lymphomaliposomal doxorubicinN-terminal pro-B-type natriuretic peptidetroponin

Identifiers

PMID33492774
PMCPMC7926012
OpenAlexW3121984050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.