Evidence map›Paper›PMID 33492742›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2021

Functional characteristics of glaucoma related arcuate defects seen on OCT en face visualisation of the retinal nerve fibre layer.

Bright S Ashimatey, Brett J King, William H Swanson

Open access · hybridAbstract read
In one paragraph

Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Predicting perimetric defects from en face maps of retinal nerve fibre layer reflectance.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2024
    Article
  4. Article
  5. Within-eye and between-subject variability for reflectance of the retinal nerve fibre layer.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bright S AshimateySchool of Optometry, Indiana University Bloomington, Indiana, USA.ORCID 0000-0002-1319-1008
Brett J KingSchool of Optometry, Indiana University Bloomington, Indiana, USA.ORCID 0000-0003-4790-3541
William H SwansonSchool of Optometry, Indiana University Bloomington, Indiana, USA.ORCID 0000-0003-1331-3658
Indiana University Bloomington · USUniversity of Southern California · US

Funding

3D RNFL Structure And High-Resolution Perimetry For Assessing Glaucomatous DamageR01EY024542 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI SWANSON, WILLIAM H. · 2014 to 2023
$3.2M
Core Support for Vision Research at Indiana UniversityP30EY019008 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI BURNS, STEPHEN A · 2009 to 2013
$2.1M
Glaucomatous damage to retinal nerve fiber bundlesR01EY028135 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI SWANSON, WILLIAM H. · 2017 to 2019
$1.2M
NEI NIH HHS P30 EY019008NEI NIH HHS R01 EY024542NEI NIH HHS R01 EY028135NIH HHS 5P30EY019008NIH HHS R01EY024542NIH HHS R01EY028135
6 · The paper itself

Abstract

purposeTo assess continuity of perimetric defects corresponding to arcuate defects seen on optical coherence tomography (OCT) en face reflectance images of the retinal nerve fibre layer (RNFL) in patients with glaucoma.

methodsSeven patients with glaucoma who had arcuate structural defects on OCT RNFL en face images were recruited. Static suprathreshold stimuli were presented along different meridians to localise perimetric defects in the corresponding hemifield. Then two contrasts, one 6 dB greater than the other, were used with kinetic perimetry to assess the slope of the defect. Findings with kinetic and 24-2 perimetry were compared.

resultsStatic perimetry found that regions of perimetric abnormality spatially corresponded with the regions of en face RNFL hyporeflectivity. Kinetic perimetry found that the slopes of the edges of the defects ranged from 3-12 dB degree

conclusionsPerimetric abnormalities and arcuate RNFL en face defects were spatially correspondent. Perimetric testing guided by OCT en face reflectance images can reveal greater functional detail of glaucomatous abnormality than 24-2 testing.

Indexed as

Visual AcuityAgedFemaleGlaucomaHumansIntraocular PressureMaleMiddle AgedNerve FibersOptic DiskReproducibility of ResultsRetinal Ganglion CellsTomography, Optical CoherenceVisual FieldsVisual Field Testsarcuate defecten face imagesglaucomaOCTperimetryretinal nerve fibre layer

Identifiers

PMID33492742
PMCPMC8248257
OpenAlexW3124437276

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.