Evidence map›Paper›PMID 33492604›Full record

ArticleNeurochemical research2021

Amentoflavone Ameliorates Memory Deficits and Abnormal Autophagy in Aβ

Bing Cao, Mengnan Zeng, Qinqin Zhang, Beibei Zhang, Yangang Cao, Yuanyuan Wu, Weisheng Feng, Xiaoke Zheng

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
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  6. Review
  7. Article
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  9. Article
  10. Bone Marrow-Derived Mesenchymal Stem Cells andStem cells international · 2023
    Article
  11. Review
  12. International journal of molecular sciences · 2022
    Article
  13. Chemical Constituents from the Flowers ofMolecules (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bing CaoHenan University of Chinese Medicine, Zhengzhou, China.
Mengnan ZengHenan University of Chinese Medicine, Zhengzhou, China.
Qinqin ZhangHenan University of Chinese Medicine, Zhengzhou, China.
Beibei ZhangHenan University of Chinese Medicine, Zhengzhou, China.
Yangang CaoHenan University of Chinese Medicine, Zhengzhou, China.
Yuanyuan WuHenan University of Chinese Medicine, Zhengzhou, China.
Weisheng FengHenan University of Chinese Medicine, Zhengzhou, China.
Xiaoke ZhengHenan University of Chinese Medicine, Zhengzhou, China. zhengxk.2006@163.com.ORCID http://orcid.org/0000-0003-3671-231X
Henan Bioengineering Technology Research Center · CNFirst Affiliated Hospital of Henan University · CN

Funding

Major Science and Technology Projects in Henan Province 171100310500the Henan province high-level personnel special support "Zhong Yuan One Thousand People Plan" - Zhongyuan Leading Talent ZYQR201810080the National Key Research and Development Project 2017YFC1702800the National Key Research and Development Project 2019YFC1708802
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease in which autophagy plays a crucial role. Amentoflavone is a flavonoid obtained from various plants and has been shown to have AD-resistant neuroprotective effects. This study investigated the role of amentoflavone on memory impairment and abnormal autophagy in amyloid-β25-35 (Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsApoptosisAutophagyBiflavonoidsCognitive DysfunctionHippocampusInflammationMemory DisordersMiceMolecular Docking SimulationNeuroprotective AgentsOxidative StressPeptide FragmentsPhosphorylationamentoflavoneAmyloid beta-Peptidesamyloid beta-protein (25-35)BiflavonoidsmTOR protein, mouseNeuroprotective AgentsPeptide FragmentsTOR Serine-Threonine KinasesAlzheimer's diseaseAmentoflavoneAutophagyAβ 25−35mTOR

Identifiers

PMID33492604
OpenAlexW3123365422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.