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ArticleHernia : the journal of hernias and abdominal wall surgery2021

Slowly absorbable mesh in contaminated incisional hernia repair: results of a French multicenter study.

D Charleux-Muller, R Hurel, T Fabacher, C Brigand, S Rohr, S Manfredelli, G Passot, P Ortega-Deballon, V Dubuisson, Y Renard and 1 more

Registry-linked trialAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04132986 (Multicenter Descriptive Study of Absorbable Biosynthetic Meshes in Contaminated Ventral Hernia Repair), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04132986 unknown statusnot on this map

Multicenter Descriptive Study of Absorbable Biosynthetic Meshes in Contaminated Ventral Hernia Repair

TypeobservationalSponsorUniversity Hospital, Strasbourg, FranceRan2019 to 2023Enrolled200ConditionsVentral Hernia Repair
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
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  8. Article
  9. Observational
  10. Mapping the therapeutic landscape in emergency incisional hernia: a scoping review.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. LTBAs in Hernia Surgery: Learning from History.World journal of surgery · 2022
    Article
  18. Slowly resorbable biosynthetic mesh: 2-year results in VHWG grade 3 hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2022
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

D Charleux-MullerDepartment of General and Digestive Surgery, Hautepierre Hospital, Strasbourg University Hospital, 2 avenue Molière, 67200, Strasbourg, France. diane.charleuxmuller@gmail.com.ORCID 0000-0003-4757-7731
R HurelDepartment of General and Digestive Surgery, Robert Debre University Hospital, University of Reims Champagne Ardenne, Reims, France.
T FabacherDepartment of Public Health, Biostatistic Laboratory, Strasbourg University Hospital, 1 place de l'Hôpital BP426, 67091, Strasbourg, France.
C BrigandDepartment of General and Digestive Surgery, Hautepierre Hospital, Strasbourg University Hospital, 2 avenue Molière, 67200, Strasbourg, France.
S RohrDepartment of General and Digestive Surgery, Hautepierre Hospital, Strasbourg University Hospital, 2 avenue Molière, 67200, Strasbourg, France.
S ManfredelliDepartment of Digestive and Oncologic Surgery, Liver Transplantation Unit, University Hospital of Besançon, Besançon, France.
G PassotDepartment of General, Digestive and Endocrine Surgery, Hospital Lyon Sud, Hospices Civils de Lyon, 165, Chemin du Grand Revoyet, 69495, Pierre Bénite, France.
P Ortega-DeballonDepartment of General and Digestive Surgery, University Hospital of Dijon, Dijon, France.
V DubuissonDepartment of Vascular and General Surgery, Bordeaux University Hospital, Place Amélie Raba Léon, 33076, Bordeaux, France.
Y RenardDepartment of General and Digestive Surgery, Robert Debre University Hospital, University of Reims Champagne Ardenne, Reims, France.
B RomainDepartment of General and Digestive Surgery, Hautepierre Hospital, Strasbourg University Hospital, 2 avenue Molière, 67200, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyze the postoperative morbidity and 1-year recurrence rate of incisional hernia repair using a biosynthetic long-term absorbable mesh in patients at higher risk of surgical infection in a contaminated surgical field.

methodsAll patients undergoing incisional hernia repair in a contaminated surgical field with the use of a biosynthetic long-term absorbable mesh (Phasix®) between May 2016 and September 2018 at six participating university centers were included in this retrospective cohort and were followed-up until September 2019. Regarding the risk of surgical infection, patients were classified according to the modified Ventral Hernia Working Group classification. Preoperative, operative and postoperative data were collected. All patients' surgical site infections (SSIs) and occurrences (SSOs) and recurrence rates were the endpoints of the study.

resultsTwo hundred and fifteen patients were included: 170 with mVHWG grade 3 (79%) and 45 with mVHWG grade 2 (21%). The SSI and SSO rates at 12 months were 22.3% and 39.5%, respectively. According to the Dindo-Clavien classification, 43 patients (20.0%) had at least one minor complication, and 57 patients (26.5%) had at least one major complication. Among the 121 patients (56.3%) having at least 1 year of follow-up, the clinical recurrence rate was 12.4%. Multivariate analysis showed that a concomitant gastrointestinal procedure was an independent risk factor for surgical infection (OR = 2.61), and an emergency setting was an independent risk factor for major complications (OR = 11.9).

conclusionThe use of a biosynthetic absorbable mesh (Phasix®) is safe in a contaminated surgical field, with satisfying immediate postoperative and 1-year results.

trial registrationThe study is registered on Clinical Trial ID: NCT04132986.

Indexed as

Hernia, VentralIncisional HerniaHerniorrhaphyHumansRecurrenceRetrospective StudiesSurgical MeshTreatment OutcomeBiosynthetic meshContaminated surgeryIncisional hernia repair

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.