Evidence map›Paper›PMID 33492512›Full record

ArticleSurgical endoscopy2021

Biliary inflammation scoring for immunoglobulin G4-related sclerosing cholangitis: an endoscopic approach with endoscopic ultrasound.

Yunlu Feng, Shengyu Zhang, Zehui Zheng, Xi Wu, Tao Guo, Qingwei Jiang, Qiang Wang, Dongsheng Wu, Aiming Yang

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. [Guidelines on the diagnosis and management of primary sclerosing cholangitis (2021)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Guideline
  2. Article
  3. Article
  4. Review
  5. [Progress on liver diseases in 2021].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yunlu Feng *Department of Gastroenterology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Wangfujing Avenue, Beijing, 100730, China.ORCID 0000-0002-2761-100X
Shengyu Zhang *Department of Gastroenterology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Wangfujing Avenue, Beijing, 100730, China.
Zehui ZhengDepartment of Gastroenterology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Wangfujing Avenue, Beijing, 100730, China.
Xi WuDepartment of Gastroenterology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Wangfujing Avenue, Beijing, 100730, China.
Tao GuoDepartment of Gastroenterology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Wangfujing Avenue, Beijing, 100730, China.
Qingwei JiangDepartment of Gastroenterology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Wangfujing Avenue, Beijing, 100730, China.
Qiang WangDepartment of Gastroenterology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Wangfujing Avenue, Beijing, 100730, China.
Dongsheng WuDepartment of Gastroenterology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Wangfujing Avenue, Beijing, 100730, China.
Aiming YangDepartment of Gastroenterology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Wangfujing Avenue, Beijing, 100730, China. yangaiming@medmail.com.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThe differential diagnosis of immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) and cholangiocarcinoma (CC) remains a clinical challenge. Imaging modalities play critical roles in the diagnosis of IgG4-SC. The present study aimed to evaluate the differential diagnosis of IgG4-SC and CC based on images of endoscopic ultrasound (EUS).

methodsThe biliary inflammation scoring (BIS) method for EUS was developed based on the comparison between images of IgG4-SC and that of cholangiocarcinoma (CC) and other acute or chronic cholangitis. In the BIS diagnostic phase, the EUS images from 66 IgG4-SC patients and 44 CC patients were blindly evaluated using the BIS methods.

resultsThe sensitivity, specificity, and accuracy of the newly established BIS in distinguishing IgG4-SC from CC were 86% [95% confidence interval (CI) 75-93%], 95% (95% CI 83-99%), and 90% (95% CI 83-94%), respectively.

conclusionEUS should be considered to be added to the workup algorithm in patients with suspected IgG4-SC as a useful diagnostic procedure. BIS is a promising diagnostic method to discriminate IgG4-SC during the ongoing endoscopy.

Indexed as

Bile Duct NeoplasmsCholangitis, SclerosingBile Ducts, IntrahepaticDiagnosis, DifferentialHumansImmunoglobulin GInflammationImmunoglobulin GCholangiocarcinomaDiagnosisEndoscopic ultrasoundIgG4-related cholangitis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.