Evidence map›Paper›PMID 33492506›Full record

ArticleSurgical endoscopy2022

Clinical utility of endoscopic submucosal dissection using the pocket-creation method with a HookKnife and preoperative evaluation by endoscopic ultrasonography for the treatment of rectal neuroendocrine tumors.

Yasuhiko Hamada, Kyosuke Tanaka, Aiji Hattori, Yuhei Umeda, Hiroki Yukimoto, Reiko Yamada, Misaki Nakamura, Hiroshi Miura, Junya Tsuboi, Masaki Katsurahara and 2 more

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yasuhiko HamadaDepartment of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.
Kyosuke TanakaDepartment of Endoscopy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. kyosuket@clin.medic.mie-u.ac.jp.ORCID 0000-0002-1402-7832
Aiji HattoriDepartment of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.
Yuhei UmedaDepartment of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.
Hiroki YukimotoDepartment of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.
Reiko YamadaDepartment of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.
Misaki NakamuraDepartment of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.
Hiroshi MiuraDepartment of Endoscopy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Junya TsuboiDepartment of Endoscopy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Masaki KatsuraharaDepartment of Endoscopy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Noriyuki HorikiDepartment of Endoscopy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Yoshiyuki TakeiDepartment of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.
Mie University Hospital · JPMie University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious endoscopic methods have been developed to remove small rectal neuroendocrine tumors (NETs). This study aimed to evaluate the clinical utility of endoscopic submucosal dissection using the pocket-creation method (ESD-PCM) with a HookKnife, following preoperative evaluation by endoscopic ultrasonography (EUS), for the treatment of rectal NETs.

methodsWe analyzed retrospectively consecutive patients who underwent ESD-PCM with a HookKnife for the removal of rectal NETs, with a size less than 10 mm, at Mie University Hospital between June 2015 and December 2019. All the rectal NETs were resected by ESD-PCM with a HookKnife. The R0 resection rate, procedure time, adverse event rate, diagnostic accuracy of tumor size and invasion depth evaluated by preoperative EUS, and follow-up outcome were evaluated retrospectively.

resultsThe study group comprised 12 patients with 12 resected lesions. The median tumor size of the resected specimens was 5 mm and the size and invasion depth of each tumor was approximately equal to that predicted by preoperative EUS. R0 resection was achieved in all cases, without adverse events. The median procedure time was 50.5 min, which did not differ from previous studies. No recurrence was observed during the median follow-up period of 34.4 months (range, 5.2-60.0 months).

conclusionsESD-PCM with a HookKnife provides a favorable clinical utility for removing rectal NETs, with high R0 resection rate and good follow-up outcome. In addition, EUS is useful for evaluating preoperatively the size and invasion depth of rectal NETs.

Indexed as

Endoscopic Mucosal ResectionNeuroendocrine TumorsRectal NeoplasmsEndosonographyHumansIntestinal MucosaRetrospective StudiesTreatment OutcomeEndoscopic resectionEndoscopic submucosal dissectionEndoscopic ultrasonographyHookKnifePocket-creation methodRectal neuroendocrine tumor

Identifiers

PMID33492506
OpenAlexW3121158520

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.