Evidence map›Paper›PMID 33492285›Full record

ArticleJournal of Alzheimer's disease : JAD2021

Long-Term Exposure to Ambient Air Pollution and Cognitive Function Among Hispanic/Latino Adults in San Diego, California.

Sindana D Ilango, Kevin Gonzalez, Linda Gallo, Matthew A Allison, Jianwen Cai, Carmen R Isasi, Dean H Hosgood, Priscilla M Vasquez, Donglin Zeng, Marion Mortamais and 2 more

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Long-term exposure to ambient OEnvironmental pollution (Barking, Essex : 1987) · 2023
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sindana D IlangoSchool of Public Health, San Diego State University, San Diego, CA, USA.
Kevin GonzalezDepartment of Neurosciences, UC San Diego, La Jolla, CA, USA.
Linda GalloDepartment of Psychology, San Diego State University, San Diego, CA, USA.
Matthew A AllisonDepartment of Family Medicine and Public Health, UC San Diego, La Jolla, CA, USA.
Jianwen CaiGillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Carmen R IsasiDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, New York, NY, USA.
Dean H HosgoodDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Priscilla M VasquezDepartment of Urban Public Health, Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA.
Donglin ZengDepartment of Biostatistics, University of North Carolina Gillings School of Global Public Health, Chapel Hill, USA.
Marion MortamaisNeuropsychiatry Epidemiological and Clinical Research, INSERM, University of Montpellier, Montpellier, France.
Hector GonzalezDepartment of Neurosciences, UC San Diego, La Jolla, CA, USA.
Tarik BenmarhniaDepartment of Family Medicine and Public Health, UC San Diego, La Jolla, CA, USA.

Funding

San Diego Resource Center for advancing Alzheimer's Research in Minority Seniors (ARMS)P30AG059299 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOHN P. ELDER, PAUL E GILBERT · 2018 to 2026
$7.4M
UCSD Integrated Cardiovascular Epidemiology FellowshipT32HL079891 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Matthew A Allison · 2007 to 2026
$6.7M
Integrating novel GIS and GPS data to assess the impact of built environments on changes in BMI, physical activity and cancer-related biomarkers in two successful weight loss interventions in women atR01CA228147 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BENMARHNIA, TARIK, JANKOWSKA, MARTA · 2019 to 2024
$2.6M
NCI NIH HHS R01 CA228147NHLBI NIH HHS T32 HL079891NIA NIH HHS P30 AG059299
6 · The paper itself

Abstract

backgroundHispanics/Latinos in the United States are more likely to live in neighborhoods with greater exposure to air pollution and are projected to have the largest increase in dementia among race/ethnic minority groups.

objectiveWe examined the associations of air pollution with performance on cognitive function tests in Hispanic/Latino adults.

methodsWe used data from the San Diego site of the Hispanic Community Health Study/Study of Latinos, an ongoing cohort of Hispanics/Latinos. This analysis focused on individuals ≥45 years of age who completed a neurocognitive battery examining overall mental status, verbal learning, memory, verbal fluency, and executive function (n = 2,089). Air pollution (PM2.5 and O3) before study baseline was assigned to participants' zip code. Logistic and linear regression were used to estimate the associations of air pollution on overall mental status and domain-specific standardized test scores. Models accounted for complex survey design, demographic, and socioeconomic characteristics.

resultsWe found that for every 10μg/m3 increase in PM2.5, verbal fluency worsened (β: -0.21 [95%CI: -0.68, 0.25]). For every 10 ppb increase in O3, verbal fluency and executive function worsened (β: -0.19 [95%CI: -0.34, -0.03]; β: -0.01 [95%CI: -0.01, 0.09], respectively). We did not identify any detrimental effect of pollutants on other domains.

conclusionAlthough we found suggestions that air pollution may impact verbal fluency and executive function, we observed no consistent or precise evidence to suggest an adverse impact of air pollution on cognitive level among this cohort of Hispanic/Latino adults.

Indexed as

CognitionAdultAgedAir PollutionCaliforniaCohort StudiesEnvironmental ExposureFemaleHispanic or LatinoHumansMaleMiddle AgedAir pollutioncognitive dysfunctioncohort studydementiahispanicslatinosozoneparticulate matter

Identifiers

PMID33492285
PMCPMC10896012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.