Evidence map›Paper›PMID 33491876›Full record

ReviewSmall (Weinheim an der Bergstrasse, Germany)2021

Nanomedicines for Endometriosis: Lessons Learned from Cancer Research.

Abraham S Moses, Ananiya A Demessie, Olena Taratula, Tetiana Korzun, Ov D Slayden, Oleh Taratula

Open access · greenAbstract readReview
In one paragraph

Review in Small (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Nanoceria as a non-steroidal anti-inflammatory drug for endometriosis theranostics.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. The Role of Nanomedicine in Benign Gynecologic Disorders.Molecules (Basel, Switzerland) · 2024
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Abraham S MosesCollege of Pharmacy, Oregon State University, 2730 S Moody Avenue, Portland, OR, 97201, USA.
Ananiya A DemessieCollege of Pharmacy, Oregon State University, 2730 S Moody Avenue, Portland, OR, 97201, USA.
Olena TaratulaCollege of Pharmacy, Oregon State University, 2730 S Moody Avenue, Portland, OR, 97201, USA.
Tetiana KorzunCollege of Pharmacy, Oregon State University, 2730 S Moody Avenue, Portland, OR, 97201, USA.
Ov D SlaydenDivision of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR, 97006, USA.
Oleh TaratulaCollege of Pharmacy, Oregon State University, 2730 S Moody Avenue, Portland, OR, 97201, USA.ORCID 0000-0002-6227-9110
Portland State University · USOregon National Primate Research Center · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Novel Nanomedicine-Based Therapeutic Approach For Treatment of Cancer CachexiaR37CA234006 · NCI · OREGON STATE UNIVERSITY · PI TARATULA, OLEH · 2019 to 2025
$3.2M
Intravascular Delivery of Nanoclusters for Treatment of Deep-Seated Cancers with Magnetic HyperthermiaR01CA237569 · NCI · OREGON STATE UNIVERSITY · PI TARATULA, OLEH · 2020 to 2024
$2.7M
A nanoparticle-based approach for surgical imaging and intraoperative treatment of endometriosisR21HD098642 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI SLAYDEN, OV D · 2020 to 2021
$462k
NCI NIH HHS R01 CA237569NCI NIH HHS R37 CA234006NICHD NIH HHS R21 HD098642NIH HHS P51 OD011092
6 · The paper itself

Abstract

Endometriosis is an incurable gynecological disease characterized by the abnormal growth of endometrium-like tissue, characteristic of the uterine lining, outside of the uterine cavity. Millions of people with endometriosis suffer from pelvic pain and infertility. This review aims to discuss whether nanomedicines that are promising therapeutic approaches for various diseases have the potential to create a paradigm shift in endometriosis management. For the first time, the available reports and achievements in the field of endometriosis nanomedicine are critically evaluated, and a summary of how nanoparticle-based systems can improve endometriosis treatment and diagnosis is provided. Parallels between cancer and endometriosis are also drawn to understand whether some fundamental principles of the well-established cancer nanomedicine field can be adopted for the development of novel nanoparticle-based strategies for endometriosis. This review provides the state of the art of endometriosis nanomedicine and perspective for researchers aiming to realize and exploit the full potential of nanoparticles for treatment and imaging of the disorder.

Indexed as

EndometriosisNeoplasmsEndometriumFemaleHumansNanomedicinePelvic Painendometriosisimagingnanomedicinesnanoparticlestherapies

Identifiers

PMID33491876
PMCPMC7928207
OpenAlexW3123286810

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.