Evidence map›Paper›PMID 33491593›Full record

Observational studyGlobal health action2021

Adaptation of WHO's generic tuberculosis patient cost instrument for a longitudinal study in Africa.

Denise Evans, Craig van Rensburg, Caroline Govathson, Olena Ivanova, Friedrich Rieß, Andrew Siroka, Abdou K Sillah, Nyanda Elias Ntinginya, Ilesh Jani, Farzana Sathar and 4 more

Abstract readObservational Study
In one paragraph

Observational study in Global health action, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Post-TB health and wellbeing.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  9. The household economic burden of drug-susceptible TB diagnosis and treatment in The Gambia.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Observational
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Denise EvansHealth Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg, South Africa.ORCID 0000-0003-0698-1228
Craig van RensburgHealth Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg, South Africa.ORCID 0000-0003-0458-3306
Caroline GovathsonHealth Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg, South Africa.ORCID 0000-0003-2595-1913
Olena IvanovaDivision of Infectious Diseases & Tropical Medicine, Klinikum of the University of Munich , Munich, Germany.ORCID 0000-0002-8276-7891
Friedrich RießDivision of Infectious Diseases & Tropical Medicine, Klinikum of the University of Munich , Munich, Germany.
Andrew SirokaHealth Financing Department, World Health Organization , Geneva, Switzerland.ORCID 0000-0002-0320-0775
Abdou K SillahMedical Research Council Unit, The Gambia at the London School of Hygiene and Tropical Medicine , Fajara, The Gambia.ORCID 0000-0001-8332-2475
Nyanda Elias NtinginyaNIMR - Mbeya Medical Research Centre , Mbeya, Tanzania.ORCID 0000-0002-1575-4521
Ilesh JaniInstituto Nacional de Sauúde (INS) , Maputo, Mozambique.ORCID 0000-0002-6880-6655
Farzana SatharAurum Institute , Johannesburg, South Africa.ORCID 0000-0002-8296-8554
Sydney RosenHealth Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg, South Africa.ORCID 0000-0002-6560-2964
Ian SanneHealth Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg, South Africa.ORCID 0000-0003-4729-3405
Andrea RachowDivision of Infectious Diseases & Tropical Medicine, Klinikum of the University of Munich , Munich, Germany.ORCID 0000-0002-4269-3699
Knut LönnrothDepartment of Global Public Health, Karolinska Institute , Stockholm, Sweden.ORCID 0000-0001-5054-8240

Funding

World Health Organization 001
6 · The paper itself

Abstract

The WHO developed a generic 'TB patient cost survey' tool and a standardized approach to assess the direct and indirect costs of TB incurred by patients and their households, estimate the proportion of patients experiencing catastrophic costs, and measure the impact of interventions to reduce patient costs. While the generic tool is a facility-based cross-sectional survey, this standardized approach needs to be adapted for longitudinal studies. A longitudinal approach may overcome some of the limitations of a cross-sectional design and estimate the economic burden of TB more precisely. We describe the process of creating a longitudinal instrument and its application to the TB Sequel study, an ongoing multi-country, multi-center observational cohort study. We adapted the cross-sectional WHO generic TB patient cost survey instrument for the longitudinal study design of TB Sequel and the local context in each study country (South Africa, Mozambique, Tanzania, and The Gambia). The generic instrument was adapted for use at enrollment (start of TB treatment; Day 0) and at 2, 6, 12 and 24 months after enrollment, time points intended to capture costs incurred for diagnosis, during treatment, at the end of treatment, and during long-term follow-up once treatment has been completed. These time points make the adapted version suitable for use in patients with either drug-sensitive or drug-resistant TB. Using the adapted tool provides the opportunity to repeat measures and make comparisons over time, describe changes that extend beyond treatment completion, and link cost survey data to treatment outcomes and post-TB sequelae.

Indexed as

TuberculosisTuberculosis, Multidrug-ResistantCost of IllnessCross-Sectional StudiesGambiaHealth Care CostsHumansLongitudinal StudiesMozambiqueSouth AfricaTanzaniaWorld Health OrganizationCatastrophic total costsincomeout-of-pocketpre-treatmentTB sequelae

Identifiers

PMID33491593
PMCPMC7850383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.