Evidence map›Paper›PMID 33491531›Full record

ReviewRenal failure2021

Immunosuppression in kidney transplant recipients with COVID-19 infection - where do we stand and where are we heading?

Ahmed Daoud, Ahmad Alqassieh, Duaa Alkhader, Maria Aurora Posadas Salas, Vinaya Rao, Tibor Fülöp, Karim M Soliman

Open access · goldAbstract readReview
In one paragraph

Review in Renal failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Coronavirus disease 2019 and renal transplantation.World journal of clinical cases · 2021
    Review
  8. Article
  9. Liver transplantation during global COVID-19 pandemic.World journal of clinical cases · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ahmed DaoudNephrology Unit, Internal Medicine Department, Kasr Alainy School of Medicine, Cairo University, Cairo, Egypt.
Ahmad AlqassiehDepartment of Surgery, Medical University of South Carolina, Charleston, SC, USA.
Duaa AlkhaderDepartment of Surgery, Medical University of South Carolina, Charleston, SC, USA.
Maria Aurora Posadas SalasDepartment of Surgery, Medical University of South Carolina, Charleston, SC, USA.
Vinaya RaoDepartment of Surgery, Medical University of South Carolina, Charleston, SC, USA.
Tibor FülöpDepartment of Medicine, Division of Nephrology, Medical University of South Carolina, Charleston, SC, USA.
Karim M SolimanDepartment of Surgery, Medical University of South Carolina, Charleston, SC, USA.
Medical University of South Carolina · USCairo University · EGRalph H. Johnson VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The appropriate immunosuppressive regimen in kidney transplant recipients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2/COVID-19) infection remains unclear. The impact of direct virus injury complicated by dysregulated hyperimmune response with overwhelming release of various cytokines in COVID-19 infected subjects contributes to the complexity of management. The largest concern of the practicing clinicians at current time is how to tailor maintenance immune-modulating therapy during active viral infection and the efficacy of the soon-to-be upcoming immunization for COVID-19. This targeted review aims to cover most of the current evidence on the effect of key maintenance immunosuppressive agents in COVID-19 infection and proposes a line of management to specific scenarios on this very rapidly evolving subject.

Indexed as

Immunosuppression TherapyKidney TransplantationAlgorithmsCOVID-19HumansImmunosuppressive AgentsRenal InsufficiencyImmunosuppressive AgentsCOVID-19; kidney transplant; bamlanivimab; immunosuppression; ivermectin; CNI.

Identifiers

PMID33491531
PMCPMC7850379
OpenAlexW3123060066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.