ReviewOral health & preventive dentistry2021
Periodontal Diseases and Adverse Pregnancy Outcomes: Review of Two Decades of Clinical Research.
Review in Oral health & preventive dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Oral health knowledge, perceptions and attitudes of pregnant women in Sub-Saharan Africa: a systematic review.BMC oral health · 2025Pooled it
- Effect of Treating Periodontal Disease in Pregnant Women to Reduce the Risk of Preterm Birth and Low Birth Weight: An Umbrella Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Periodontal Disease and Alzheimer's: Insights from a Systematic Literature Network Analysis.The journal of prevention of Alzheimer's disease · 2024Pooled it
- Clinical practice guidelines and consensus statements integrating periodontal disease into cardiology, diabetes care and dementia: A scoping review and gap analysis.Medicina oral, patologia oral y cirugia bucal · 2026Article
- A scientometric analysis of research related to the 'oral-placental axis' hypothesis: current status, hotspots, and future directions.Frontiers in cellular and infection microbiology · 2026Review
- Mathematical Modeling of Obstetric Variables: Influence of COVID-19, Periodontal Disease and Dental Care During Pregnancy.Biomedicines · 2025Article
- Periodontal diseases among pregnant adolescents and young women in Nigeria: a scoping review.BMC oral health · 2025Article
- Knowledge of the Association Between Periodontal Diseases and Adverse Pregnancy Outcomes among Pregnant Women in Ivory Coast: A Cross-Sectional Study.Oral health & preventive dentistry · 2024Article
- Article
- A prospective study on maternal periodontal diseases and neonatal adverse outcomes.Acta odontologica Scandinavica · 2024Article
- The Impact of Periodontal Disease on Preterm Birth and Preeclampsia.Journal of personalized medicine · 2024Review
- Exploring the composition of placental microbiome and its potential origin in preterm birth.Frontiers in cellular and infection microbiology · 2024Article
- Oral and periodontal assessment at the first trimester of pregnancy: The PERISCOPE longitudinal study.Acta obstetricia et gynecologica Scandinavica · 2023Observational
- The association of employment status and unwanted job loss with maternal oral health experiences: findings from the pregnancy risk assessment monitoring system.BMC oral health · 2023Article
- Association between the Risk of Preterm Birth and Low Birth Weight with Periodontal Disease in Pregnant Women: An Umbrella Review.Dentistry journal · 2023Review
- Review
- Association Between Periodontitis and Preterm Birth in a Cohort of Pregnant Women in Ivory Coast.Oral health & preventive dentistry · 2022Article
- The Association between Maternal Periodontitis and Preterm Birth: A Case-Control Study in a Low-Resource Setting in Sudan, Africa.Medicina (Kaunas, Lithuania) · 2022Article
- Periodontal Inflamed Surface Area Is Associated With Increased Gestational Blood Pressure and Uric Acid Levels Among Pregnant Women From Rural North China.Frontiers in cardiovascular medicine · 2022Article
- Periodontal disease in pregnancy and adverse pregnancy outcomes: Progress in related mechanisms and management strategies.Frontiers in medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The aim of this study was to review the literature and chart the clinical studies that have focused on periodontal diseases and adverse pregnancy outcomes since 1996. Materials and Methods: Medline, Cinahl, and Cochrane databases were searched for original studies focused on pregnancy outcomes and periodontal status in humans. The most recent search was conducted on April 30, 2020. Results: Of the 633 articles identified, 232 articles (n = 119,774 participants) were selected for analysis. The majority of studies highlighted a statistically significant association between periodontal diseases and preterm birth (71 of 111 articles; 63.96%), low birth weight (46 of 64 articles; 71.87%), preterm low birth weight (29 of 49 articles; 59.18%), preeclampsia (31 of 45 articles; 68.89%) and other pregnancy complications, such as preterm, prelabor rupture of membranes (17 of 26 articles; 65.38%). Geographical analysis revealed that clinical studies were conducted in 51 countries, primarily in the United States (42 studies, 18.10%), Brazil (33 studies, 14.22%) and India (25 studies, 10.78%). Irrespective of geographical location, analysis showed various degrees of evidence of a relationship between periodontal diseases and adverse pregnancy outcomes. Conclusion: The majority of the studies found a statistically significant link between periodontal diseases and some complications of pregnancy. The strength of such a link varies according to type of study, type of variable and outcome measure selected.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.