Evidence map›Paper›PMID 33491323›Full record

Trial reportJournal of cosmetic dermatology2021

Almond consumption increased UVB resistance in healthy Asian women.

Jason N Li, Susanne M Henning, Gail Thames, Omar Bari, Patrick T Tran, Chi-Hong Tseng, David Heber, Jenny Kim, Zhaoping Li

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of cosmetic dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Natural Modulators of Key Signaling Pathways in Skin Inflammageing.Clinical, cosmetic and investigational dermatology · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jason N LiDepartment of Medicine, David Geffen School of Medicine, Center for Human Nutrition, Los Angeles, CA, USA.
Susanne M HenningDepartment of Medicine, David Geffen School of Medicine, Center for Human Nutrition, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0003-1085-7588
Gail ThamesDepartment of Medicine, David Geffen School of Medicine, Center for Human Nutrition, Los Angeles, CA, USA.
Omar BariDivision of Dermatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Patrick T TranDivision of Dermatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Chi-Hong TsengDepartment of Statistics Core, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
David HeberDepartment of Medicine, David Geffen School of Medicine, Center for Human Nutrition, Los Angeles, CA, USA.
Jenny KimDepartment of Medicine, David Geffen School of Medicine, Center for Human Nutrition, Los Angeles, CA, USA.
Zhaoping LiDepartment of Medicine, David Geffen School of Medicine, Center for Human Nutrition, Los Angeles, CA, USA.
University of California, Los Angeles · US

Funding

Almond Board of California
6 · The paper itself

Abstract

backgroundAlmonds are a rich source of phenolic and polyphenolic compounds, which have antioxidant activity. In vitro and in vivo studies have demonstrated that topical application of almond oil and almond skin extract reduces UVB-induced photoaging. Ultraviolet-B (UVB) protection by oral almond consumption has not been previously studied in humans.

objectivesTo investigate whether oral almond consumption can increase resistance to UVB radiation and reduce skin aging in healthy Asian women.

methodsThirty-nine female participants (18-45 years) with Fitzpatrick skin type II-IV were randomly assigned to consume either 1.5 oz of almonds or 1.8 oz of pretzels daily for 12 weeks. Minimal erythema dose (MED) was determined using a standardized protocol, which determined the minimal radiation needed to induce erythema on the inner arm following UVB exposure. Facial skin texture was evaluated by two dermatologists using the Clinician's Erythema Assessment scale and Allergan Roughness scale. Facial melanin index, hydration, sebum, and erythema were determined using a cutometer.

resultsThe MED was increased in the subjects consuming almonds compared to the control group consuming pretzels. There were no differences noted between the groups consuming almonds versus pretzels in Allergan roughness, melanin, hydration, or sebum on facial skin.

conclusionsOur findings suggest that daily oral almond consumption may lead to enhanced protection from UV photodamage by increasing the MED.

Indexed as

Prunus dulcisSkin AgingErythemaFemaleHumansSkinUltraviolet Raysalmondfacial skin textureminimal erythema doserandomized controlled trialUVB skin exposure

Identifiers

PMID33491323
PMCPMC8451851
OpenAlexW3126139718

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.