Evidence map›Paper›PMID 33491191›Full record

ArticleThe EMBO journal2021

Centrosomes: Please keep your social distance!

Lenno Krenning, Jonne A Raaijmakers, René H Medema

Open access · bronzeAbstract readComment
In one paragraph

Article in The EMBO journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lenno KrenningDivision of Cell Biology, Oncode Institute, Netherlands Cancer Institute, Amsterdam, the Netherlands.ORCID 0000-0001-6696-0512
Jonne A RaaijmakersDivision of Cell Biology, Oncode Institute, Netherlands Cancer Institute, Amsterdam, the Netherlands.ORCID 0000-0003-1759-8347
René H MedemaDivision of Cell Biology, Oncode Institute, Netherlands Cancer Institute, Amsterdam, the Netherlands.ORCID 0000-0002-6754-0381
The Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate control of centrosome number is essential for proper chromosome segregation, and it is well established that centrosome abnormalities can trigger a p53-dependent cell cycle arrest. Two new studies published in The EMBO Journal demonstrate how PIDD1 is recruited to centrosomes and that the localization of PIDD1 to distal appendages of centrosomes is required for PIDDosome activation at clustered supernumerary centrosomes.

Indexed as

CentrosomeChromosome SegregationCell Cycle Checkpoints

Identifiers

PMID33491191
PMCPMC7883290
OpenAlexW3125134778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.