ArticleIntensive care medicine experimental2021
Lung ultrasound and computed tomography to monitor COVID-19 pneumonia in critically ill patients: a two-center prospective cohort study.
Article in Intensive care medicine experimental, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Ultrasound findings of lung ultrasonography in COVID-19: A systematic review.European journal of radiology · 2022Pooled it
- Review
- Accuracy of lung ultrasound in the diagnosis of acute respiratory distress syndrome: a systematic review and meta-analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Article
- Predictive role of lung ultrasound score for mortality risk of patients with severe pneumonia: a systematic review and meta-analysis.Journal of thoracic disease · 2026Article
- Synergistic Imaging: Combined Lung Ultrasound and Low-Dose Chest CT for Quantitative Assessment of COVID-19 Severity-A Prospective Observational Study.Diagnostics (Basel, Switzerland) · 2025Article
- ESICM-ESPNIC international expert consensus on quantitative lung ultrasound in intensive care.Intensive care medicine · 2025Article
- The Role of POCUS to Face COVID-19: A Narrative Review.Journal of clinical medicine · 2024Review
- Correlation between Serum Biomarkers and Lung Ultrasound in COVID-19: An Observational Study.Diagnostics (Basel, Switzerland) · 2024Article
- Lung ultrasound score for the assessment of lung aeration in ARDS patients: comparison of two approaches.Ultrasound international open · 2024Article
- Effects of nurse delivered thoracic ultrasound on management of adult intensive care unit patients: A prospective observational study.International journal of nursing studies advances · 2023Article
- Article
- The diagnostic accuracy of lung ultrasound to determine PiCCO-derived extravascular lung water in invasively ventilated patients with COVID-19 ARDS.The ultrasound journal · 2023Article
- The value of lung ultrasound in COVID-19 pneumonia, verified by high resolution computed tomography assessed by artificial intelligence.BMC infectious diseases · 2023Observational
- Concise Versus Extended Lung Ultrasound Score to Monitor Critically Ill Patients With COVID-19.Respiratory care · 2023Observational
- Monitoring of pulmonary involvement in critically ill COVID-19 patients - should lung ultrasound be preferred over CT?The ultrasound journal · 2023Article
- Lung ultrasound to predict gas-exchange response to prone positioning in COVID-19 patients: A prospective study in pilot and confirmation cohorts.Journal of critical care · 2023Observational
- Point-of-care Lung Ultrasound, Lung CT and NEWS to Predict Adverse Outcomes and Mortality in COVID-19 Associated Pneumonia.Journal of intensive care medicine · 2022Article
- The RALE Score Versus the CT Severity Score in Invasively Ventilated COVID-19 Patients-A Retrospective Study Comparing Their Prognostic Capacities.Diagnostics (Basel, Switzerland) · 2022Article
- The Role of Lung Ultrasound Monitoring in Early Detection of Ventilator-Associated Pneumonia in COVID-19 Patients: A Retrospective Observational Study.Journal of clinical medicine · 2022Article
- Comparison of two different lung ultrasound imaging protocols in COVID-19 pneumonia.Ultrasonography (Seoul, Korea) · 2022Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLung ultrasound can adequately monitor disease severity in pneumonia and acute respiratory distress syndrome. We hypothesize lung ultrasound can adequately monitor COVID-19 pneumonia in critically ill patients.
methodsAdult patients with COVID-19 pneumonia admitted to the intensive care unit of two academic hospitals who underwent a 12-zone lung ultrasound and a chest CT examination were included. Baseline characteristics, and outcomes including composite endpoint death or ICU stay > 30 days were recorded. Lung ultrasound and CT images were quantified as a lung ultrasound score involvement index (LUSI) and CT severity involvement index (CTSI). Primary outcome was the correlation, agreement, and concordance between LUSI and CTSI. Secondary outcome was the association of LUSI and CTSI with the composite endpoints.
resultsWe included 55 ultrasound examinations in 34 patients, which were 88% were male, with a mean age of 63 years and mean P/F ratio of 151. The correlation between LUSI and CTSI was strong (r = 0.795), with an overall 15% bias, and limits of agreement ranging - 40 to 9.7. Concordance between changes in sequentially measured LUSI and CTSI was 81%. In the univariate model, high involvement on LUSI and CTSI were associated with a composite endpoint. In the multivariate model, LUSI was the only remaining independent predictor.
conclusionsLung ultrasound can be used as an alternative for chest CT in monitoring COVID-19 pneumonia in critically ill patients as it can quantify pulmonary involvement, register changes over the course of the disease, and predict death or ICU stay > 30 days.
trial registrationNTR, NL8584. Registered 01 May 2020-retrospectively registered, https://www.trialregister.nl/trial/8584.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.