SynthesisThe journal of nutrition, health & aging2021
Sarcopenia as a Risk Factor for Future Hip Fracture: A Meta-Analysis of Prospective Cohort Studies.
Synthesis in The journal of nutrition, health & aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Effectiveness of different modes of digital health interventions for sarcopenia in older adults: a systematic review and network meta-analysis.BMC geriatrics · 2026Pooled it
- Effects of digital health interventions on muscle mass, muscle strength, and physical function in older adults with sarcopenia: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Characteristics of fragility hip fracture-related falls in the older adults: A systematic review.The journal of nutrition, health & aging · 2024Pooled it
- Improved prediction of hip fracture using multi-faceted biomechanical computed tomography.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Article
- Intrinsic capacity trajectory and hip fracture risk in Chinese middle-aged and older adults: a 10-year retrospective cohort study.Scientific reports · 2026Article
- Women with Graves' Disease Have Altered Proximal Hip Geometry, Trabecular Bone Score and Body Composition Parameters: A Case-Control Study from Southern India.Calcified tissue international · 2026Article
- Effects of General Anesthesia Versus Spinal Anesthesia on Early Postoperative Cognition and 30-Day Activities of Daily Living in Elderly Hip Fracture Patients in a Chinese Plateau Region.International journal of general medicine · 2026Article
- Aging-related muscle mass decline in hip fracture patients across age groups.Annals of medicine · 2025Article
- Sarcopenia as a predictor of negative health outcomes in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.Diabetology & metabolic syndrome · 2025Review
- Association between sarcopenia and falls, fractures, hospital readmission, and all-cause mortality in older adults with endocrine disorders: a longitudinal study of aging in China.BMC musculoskeletal disorders · 2025Article
- The Sonographic Evaluation of Abductor Injury After Intramedullary Nailing for the Hip Fractures.Journal of clinical medicine · 2025Article
- Sarcopenia is associated with increased hip fracture risk among middle-aged and elderly Chinese adults in longitudinal analysis of CHARLS data.Scientific reports · 2025Article
- Machine learning-based online web calculator predicts the risk of sarcopenic obesity in older adults.Aging clinical and experimental research · 2025Article
- Association between sarcopenia index and the risk of second hip fracture in older adults.The journal of nutrition, health & aging · 2025Article
- Total Distance Walked After Hip Surgery Identifies Older Patients With Sarcopenia.Nursing & health sciences · 2025Observational
- Sarcopenia and its associated factors among hip fracture patients admitted to a North African (Egyptian) Level one trauma center, a cross-sectional study.Journal of orthopaedic surgery and research · 2025Article
- Assessing bone and muscle health and their association in a Mongolian population aged 40 and older: a pioneering observational study.Archives of osteoporosis · 2025Observational
- Association of a Combined Body Mass Index and Regional Body Fat Percentage Metric With Fragility Fracture Risk: Evidence from a Large Observational Cohort.Journal of cachexia, sarcopenia and muscle · 2025Observational
- Relationship Between Body Mass Index and Low Skeletal Muscle Mass in Adults Based on NHANES 2011-2018.Scientific reports · 2025Article
- Prevention of Sarcopenia.Advances in experimental medicine and biology · 2025Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveOur study aims to determine whether sarcopenia is a predictive factor of future hip fractures.
designSystematic review and meta-analysis. Set: We searched for potentially suitable articles in PubMed, Cochrane library, Medline and EMBASE from inception to March 2020. The quality of the research was assessed by the Newcastle-Ottawa Scale (NOS). Finally, a meta-analysis was conducted with the Stata software.
participantsOlder community-dwelling residents. MEASUREMENTS: Hip fracture due to sarcopenia.
resultsWe retrieved 2129 studies through our search strategy, and five studies with 23,359 individuals were analyzed in our pooled analyses. Sarcopenia increases the risk of future hip fractures with a pooled hazard ratio (HR) of 1.42 (95% CI: 1.18-1.71, P <0.001, I2 = 37.7%). In addition, in subgroup analyses based on different definitions of sarcopenia, sarcopenia was associated with the risk of future hip fractures with the Asian Working Group for Sarcopenia (AWGS) criteria with a pooled HR of 2.13(95% CI: 1.33-3.43). When subgroup analyses were conducted by sex, sarcopenia was associated with the risk for future hip fractures in females with pooled HRs of 1.69 (95% CI: 1.18-2.43). Sarcopenia was associated with the risk of future hip fractures in the group with a follow-up period of more than 5 years, with a pooled HR of 1.32 (95% CI: 1.08-1.61), and in the group with a follow-up period of less than 5 years, with a pooled HR of 2.13 (95% CI: 1.33-3.43).
conclusionsSarcopenia could significantly increase the risk of future hip fracture in old people; thus, it is necessary to prevent hip fractures in individuals with sarcopenia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.