Evidence map›Paper›PMID 33490948›Full record

ArticleEpilepsy & behavior reports2021

Association of early-onset epileptic encephalopathy with involuntary movements - Case series and literature review.

Atsuko Arisaka, Mitsuko Nakashima, Satoko Kumada, Kenji Inoue, Hiroya Nishida, Hideaki Mashimo, Hirofumi Kashii, Mitsuhiro Kato, Koichi Maruyama, Akihisa Okumura and 3 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Epilepsy & behavior reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
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  4. Genes · 2023
    Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Atsuko ArisakaDepartment of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo, Japan.
Mitsuko NakashimaDepartment of Biochemistry, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Satoko KumadaDepartment of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo, Japan.
Kenji InoueDepartment of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo, Japan.
Hiroya NishidaDepartment of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo, Japan.
Hideaki MashimoDepartment of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo, Japan.
Hirofumi KashiiDepartment of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo, Japan.
Mitsuhiro KatoDepartment of Pediatrics, Showa University School of Medicine, Shinagawa, Tokyo, Japan.
Koichi MaruyamaDepartment of Pediatric Neurology, Aichi Developmental Disability Center Central Hospital, Kasugai, Aichi, Japan.
Akihisa OkumuraDepartment of Pediatrics, Aichi Medical University, Nagakute, Aichi, Japan.
Hirotomo SaitsuDepartment of Biochemistry, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Naomichi MatsumotoDepartment of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan.
Mitsumasa FukudaDepartment of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo, Japan.
Tokyo Metropolitan Neurological Hospital · JPHamamatsu University School of Medicine · JPAichi Developmental Disability Center · JPAichi Medical University · JPShowa University · JPYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epileptic-dyskinetic encephalopathies are rare epilepsies characterized by early-onset epileptic encephalopathies (EOEEs) with involuntary movement. Herein, we investigated the impact of gene variants in epileptic-dyskinetic encephalopathies. Four independent patients from four families who exhibited involuntary movements were recruited from Tokyo Metropolitan Neurological Hospital. The inclusion criteria were as follows: onset within 1 year after birth, frequent seizures, severe developmental delay and accompanying involuntary movements. We detected four genetic mutations, including

Indexed as

ACTH, adrenocorticotropic hormoneEarly-onset epileptic encephalopathyEEG, electroencephalographyEMG, electromyographyEOEEEOEEs, early-onset epileptic encephalopathiesEpileptic-dyskinetic encephalopathyEpileptic seizureGenetic variantInvoluntary movementMRI, magnetic resonance imaging

Identifiers

PMID33490948
PMCPMC7808918
OpenAlexW3114233116

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.