Evidence map›Paper›PMID 33490914›Full record

ArticleiScience2021

Prototype multi-biomarker test for point-of-care leprosy diagnostics.

Anouk van Hooij, Elisa M Tjon Kon Fat, Danielle de Jong, Marufa Khatun, Santosh Soren, Abu Sufian Chowdhury, Johan Chandra Roy, Khorshed Alam, Jong-Pill Kim, Jan Hendrik Richardus and 2 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Performance of 2 Finger-Stick Blood Tests to Triage Adults With Symptoms of Pulmonary Tuberculosis: A Prospective Multisite Diagnostic Accuracy Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Trial
  4. Article
  5. Article
  6. Leprosy research updates: Shaping the future of global health.The Indian journal of medical research · 2025
    Article
  7. Article
  8. Article
  9. Leprosy.Nature reviews. Disease primers · 2024
    Review
  10. Target product profiles: leprosy diagnostics.Bulletin of the World Health Organization · 2024
    Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Anouk van HooijDepartment of Infectious Diseases Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, the Netherlands.
Elisa M Tjon Kon FatDepartment of Cell and Chemical Biology, Leiden University Medical Center, the Netherlands.
Danielle de JongDepartment of Cell and Chemical Biology, Leiden University Medical Center, the Netherlands.
Marufa KhatunRural Health Program, The Leprosy Mission International Bangladesh, Nilphamari, Bangladesh.
Santosh SorenRural Health Program, The Leprosy Mission International Bangladesh, Nilphamari, Bangladesh.
Abu Sufian ChowdhuryRural Health Program, The Leprosy Mission International Bangladesh, Nilphamari, Bangladesh.
Johan Chandra RoyRural Health Program, The Leprosy Mission International Bangladesh, Nilphamari, Bangladesh.
Khorshed AlamRural Health Program, The Leprosy Mission International Bangladesh, Nilphamari, Bangladesh.
Jong-Pill KimInstitute for Leprosy Research, Korean Hansen Welfare Association, Gyeonggi-do, South Korea.
Jan Hendrik RichardusDepartment of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Annemieke GelukDepartment of Infectious Diseases Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, the Netherlands.
Paul L A M CorstjensDepartment of Cell and Chemical Biology, Leiden University Medical Center, the Netherlands.
Leiden University Medical Center · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To end the decade-long, obstinately stagnant number of new leprosy cases, there is an urgent need for field-applicable diagnostic tools that detect infection with

Indexed as

Applied MicrobiologyBiotechnologyDiagnostic Technique in Health Technology

Identifiers

PMID33490914
PMCPMC7807156
OpenAlexW3118011856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.