ArticleAdvances in radiation oncology
Influence of intra- and interfraction motion on planning target volume margin in liver stereotactic body radiation therapy using breath hold.
Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 15 citations in OpenAlex.
- Potential of isotoxic dose escalation with robustly optimized VMAT and IMPT for large hepatocellular carcinoma according to baseline liver function.Journal of applied clinical medical physics · 2026Article
- Implementation of surface-guided radiotherapy for motion management in liver SBRT: A scoping review and clinical workflow development.Technical innovations & patient support in radiation oncology · 2026Article
- A glimpse into the CyberKnife robotic radiosurgery system: technical specifications and developments during thirty years.Frontiers in oncology · 2026Review
- A systematic review of tumour position reproducibility and stability in breath-hold for radiation therapy of the upper abdomen.Physics and imaging in radiation oncology · 2025Review
- Clinical implementation and evaluation of stereotactic liver radiotherapy in inspiration breath-hold using nasal high-flow therapy and surface guidance.The British journal of radiology · 2024Article
- Feasibility of a portable respiratory training system with a gyroscope sensor.The British journal of radiology · 2024Article
- SBRT for Liver Tumors: What the Interventional Radiologist Needs to Know.Seminars in interventional radiology · 2024Review
- Intra- and inter-fraction breath-hold variations and margins for radiotherapy of abdominal targets.Physics and imaging in radiation oncology · 2023Article
- Online verification of breath-hold reproducibility using kV-triggered imaging for liver stereotactic body radiation therapy.Journal of applied clinical medical physics · 2023Article
- Article
- A review of surface guidance in extracranial stereotactic body radiotherapy (SBRT/SABR) for set-up and intra-fraction motion management.Technical innovations & patient support in radiation oncology · 2022Article
- Interfractional Liver Positional Motion Under Exhaled Breath Holding Based on Cone Beam Computed Tomography.In vivo (Athens, Greece)Article
- Evaluation of Residual Liver Motion Using Multiphase Computed Tomography in Stereotactic Body Radiotherapy: A Comparison of Three Motion Management Techniques.Journal of medical physicsArticle
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to investigate intra- and interfraction motion during liver stereotactic body radiation therapy for the purpose of planning target volume (PTV) margin estimation, comparing deep inspiration breath hold (DIBH) and deep expiration breath hold (DEBH). METHODS AND MATERIALS: Pre- and posttreatment kV cone beam computed tomography (CT) images were acquired for patients with liver cancer who were treated using stereotactic body radiation therapy with DIBH or DEBH. A total of 188 images were analyzed from 18 patients. Positioning errors were determined based on a comparison with planning CT images and matching to the liver. Treatment did not proceed until errors were ≤3 mm. Standard deviations of random and systematic errors resulting from this image matching process were used to calculate PTV margin estimates.
resultsDIBH errors are generally larger than DEBH errors, especially in the anterior-posterior and superior-inferior directions. Posttreatment errors tend to be larger than pretreatment errors, especially for DIBH. Standard deviations of random errors are larger than those of systematic errors. Considering both pre- and posttreatment cone beam CT images, PTV margins for DIBH and DEBH are estimated as anterior-posterior, superior-inferior, right-left = (5.7, 6.3, 3.0) mm and (3.1, 3.4, 2.8) mm, respectively.
conclusionsThis study suggests that DEBH results in more reproducible target positioning, which could in turn justify the use of smaller PTV margins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.