Evidence map›Paper›PMID 33490618›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2021

Determinants of long-term function and general well-being in patients with an ileoanal pouch.

Angela J Khera, Janet W Chase, Michael Salzberg, Alexander J V Thompson, Rodney J Woods, Amy Wilson-O'Brien, Michael A Kamm

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Angela J KheraDepartment of Gastroenterology St Vincent's Hospital Melbourne Victoria Australia.ORCID https://orcid.org/0000-0002-9927-7047
Janet W ChaseDepartment of Gastroenterology St Vincent's Hospital Melbourne Victoria Australia.
Michael SalzbergFaculty of Medicine, Dentistry and Health Sciences The University of Melbourne Melbourne Victoria Australia.
Alexander J V ThompsonDepartment of Gastroenterology St Vincent's Hospital Melbourne Victoria Australia.
Rodney J WoodsDepartment of Colorectal Surgery St Vincent's Hospital Melbourne Victoria Australia.
Amy Wilson-O'BrienFaculty of Medicine, Dentistry and Health Sciences The University of Melbourne Melbourne Victoria Australia.
Michael A KammDepartment of Gastroenterology St Vincent's Hospital Melbourne Victoria Australia.ORCID https://orcid.org/0000-0003-3319-7199
The University of Melbourne · AUSt Vincent's Hospital Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimFecal incontinence and/or evacuation difficulty are common after ileoanal pouch surgery. This study aimed to determine whether the development of these symptoms can be predicted so that preventive measures might be instituted.

methodsA consecutive series of 46 patients with ulcerative colitis (median age at surgery, 41 years; 50% female) and a functioning pouch for a duration ≥12 months was included. Assessment utilized medical record review and questionnaires on pre- and postoperative bowel function, quality of life, and psychological well-being. Pouch function was assessed by the Colorectal Functional Outcome score (0 = no impairment, 100 = worst impairment). Good pouch function was defined as a score ≤24.

resultsFecal incontinence occurred in 67% preoperatively and 54% postoperatively; evacuation difficulty occurred in 65% and preoperatively and 85% postoperatively. The postoperative median Colorectal Functional Outcome score was 20 (range 2-74), with 44% of patients >24 (poor pouch function). Preoperative nocturnal fecal incontinence (odds ratio [OR] 4.92, 95% confidence interval [CI] 1.2-19.4,

conclusionsFunctional bowel symptoms are common before and after pouch surgery and are associated with the impairment of patient-reported outcomes. Preoperative nocturnal fecal incontinence predicts poor pouch function. Therapeutic focus on continence, bowel evacuation, psychological well-being, and quality of life should begin before surgery.

Indexed as

evacuation difficultyfecal incontinencefunctional outcomeileoanal pouch

Identifiers

PMID33490618
PMCPMC7812478
OpenAlexW3103013371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.