ArticleBioMed research international2021
Effects of Remimazolam and Propofol on Ca
Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- JSA guideline for management of malignant hyperthermia in 2025.Journal of anesthesia · 2026Guideline
- RemimazolamPeerJ · 2026Pooled it
- Comparison of Remimazolam and Propofol on Post-Induction Hypotension in Elderly Hypertensive Patients: A Randomized Controlled Trial.Drug design, development and therapy · 2025Trial
- Anesthesia Management in a Patient With a History of Fulminant Malignant Hyperthermia and a Homozygous RYR1 p.Arg530His Variant Undergoing Laparoscopic Surgery: A Case Report.The American journal of case reports · 2026Article
- Evaluation of clinically relevant sevoflurane concentrations in the development of malignant hyperthermia in an Ryr1 mutant mouse model.BMC anesthesiology · 2026Article
- Remimazolam as an Adjunct to General Anesthesia During Surgery for Congenital Heart Disease in a Pediatric Patient With a Family History of Malignant Hyperthermia.Journal of medical cases · 2025Article
- Successful sedation with remimazolam and alfentanil in a child susceptible to malignant hyperthermia: a case report.BMC anesthesiology · 2025Article
- Propofol binds and inhibits skeletal muscle ryanodine receptor 1.British journal of anaesthesia · 2024Article
- Remimazolam-based total intravenous anesthesia in a patient with a confirmed diagnosis of malignant hyperthermia: a case report.JA clinical reports · 2024Article
- Clinical Application and Research Progress of Remimazolam for Pediatric Patients.Drug design, development and therapy · 2024Review
- Article
- Remimazolam Compared to Propofol During Hysteroscopy: A Safety and Efficacy Analysis.Pain and therapy · 2023Article
- Use of remimazolam in living donor liver transplantation: a case report.JA clinical reports · 2022Article
- Remimazolam in a Pediatric Patient With a Suspected Family History of Malignant Hyperthermia.Journal of medical cases · 2022Article
- Characterization of intracellular calcium mobilization induced by remimazolam, a newly approved intravenous anesthetic.PloS one · 2022Article
- General anesthesia with remimazolam in a patient with clinically suspected malignant hyperthermia.JA clinical reports · 2021Article
- Remimazolam: Non-Clinical and Clinical Profile of a New Sedative/Anesthetic Agent.Frontiers in pharmacology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe investigated the potential safety of remimazolam and propofol in malignant hyperthermia- (HM-) susceptible patients using ryanodine receptor 1- (RYR1-) expressing human embryonic kidney- (HEK-) 293 cells.
methodsWe compared the enhanced responsiveness of HEK-293 cells expressing wild-type
resultsRemimazolam and propofol did not promote the caffeine-induced increase in intracellular Ca
conclusionsThe increase in intracellular Ca
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.