Evidence map›Paper›PMID 33490243›Full record

SynthesisBioMed research international2020

Miscarriage on Endometriosis and Adenomyosis in Women by Assisted Reproductive Technology or with Spontaneous Conception: A Systematic Review and Meta-Analysis.

Yangxue Huang, Xianhong Zhao, Yiyuan Chen, Jie Wang, Weilin Zheng, Lixing Cao

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05418140 (Adenomyosis and Pregnancy Outcomes in Women Undergoing Assisted Reproductive Technology Treatment), which is not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05418140 unknown statusnot on this mapstarted 2022, after this paper: background citation

Adenomyosis and Pregnancy Outcomes in Women Undergoing Assisted Reproductive Technology Treatment: a Prospective Multicentre Cohort Study (AdAPT-ART)

TypeobservationalSponsorCARE Fertility UKRan2022 to 2025Enrolled828ConditionsAdenomyosis, Infertility, ART, Pregnancy LossArmsUltrasound diagnosis of adenomyosis
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The Impact of Endometriosis on Pregnancy.Journal of personalized medicine · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Adenomyosis and infertility.Journal of assisted reproduction and genetics · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yangxue HuangGuangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.ORCID https://orcid.org/0000-0002-2876-3590
Xianhong ZhaoGuangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Yiyuan ChenGuangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Jie WangGuangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Weilin ZhengGuangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Lixing CaoGynecology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.ORCID https://orcid.org/0000-0001-6602-7730
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the past several years, there has been an increasing concern on miscarriage caused by endometriosis or adenomyosis. However, the results reported by different studies remain controversial. The present study is aimed at assessing the impact of endometriosis and adenomyosis on miscarriage. MATERIALS AND

methodsSearches were carried out in PubMed, Embase, and the Cochrane library for studies published from inception until February 29, 2020. The investigators included studies that evaluated miscarriage risk in pregnant women with endometriosis or adenomyosis by assisted reproductive technology (ART), or with spontaneous conception (SC). Miscarriage (<28 weeks) was the primary outcome. The secondary outcomes were antepartum hemorrhage (APH), postpartum hemorrhage (PPH), preterm birth, low birthweight, placenta praevia, placental abruption, ectopic pregnancy, stillbirth, gestational diabetes, preeclampsia, and intrauterine growth restriction (IUGR). Endnote was used for the study collection, and the data analyses were carried out by two authors using Review Manager version 5.2.

resultsThirty-nine studies, which is comprised of 697,984 women, were included in the present study. Miscarriage risk increased in women with endometriosis in SC (OR: 1.81, 95% CI: 1.44-2.28,

conclusionWomen with endometriosis had an augmented miscarriage risk in SC and a similar miscarriage risk during ART. Adenomyosis was associated with miscarriage in pregnant women using ART.

Indexed as

Abortion, SpontaneousAdenomyosisEndometriosisFemaleHumansPregnancyPregnancy ComplicationsReproductive Techniques, Assisted

Identifiers

PMID33490243
PMCPMC7787757
OpenAlexW3110971725

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.