ArticleAnnals of translational medicine2020
Trends in cancer incidence and mortality rates in the United States from 1975 to 2016.
Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Insights into US life expectancy stagnation from birth cohort mortality dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Low medical trust predicts delays in seeking care among U.S. individuals who smoke: Findings from the 2022 HINTS.Preventive medicine reports · 2026Article
- Trend analysis of cancer mortality and years of life lost in the South of Iran 2004-2019. Joinpoint regression analysis.BMC cancer · 2025Article
- Survival benefit of primary tumor resection in pancreatic neuroendocrine tumors with unresectable liver metastases: A meta-analysis.World journal of gastrointestinal surgery · 2025Article
- The global burden of stomach cancer and its risk factors from 1990 to 2021: findings from the Global Burden of Disease Study 2021.BMC public health · 2025Article
- Public Health Measures Largely Responsible for Decline in U.S. Cancer Mortality.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- A Pan-Cancer Analysis of Age and Sex Differences in Cancer Incidence and Survival in the United States, 2001-2020.Cancers · 2025Article
- Cancer morbidity and mortality trends in Trinidad and Tobago (2008-2018).Journal of health, population, and nutrition · 2023Article
- Expanding access to early phase trials: the CATCH-UP.2020 experience.JNCI cancer spectrum · 2023Article
- The global, regional and national burden of stomach cancer and its attributable risk factors from 1990 to 2019.Scientific reports · 2022Article
- Oncology Simulation Model: A Comprehensive and Innovative Approach to Estimate and Project Prevalence and Survival in Oncology.Clinical epidemiology · 2022Article
- Surveillance of the Incidence and Mortality of Oral and Pharyngeal, Esophageal, and Lung Cancer in Nevada: Potential Implications of the Nevada Indoor Clean Air Act.International journal of environmental research and public health · 2021Article
- Germline Genetics of Prostate Cancer: Prevalence of Risk Variants and Clinical Implications for Disease Management.Cancers · 2021Review
- Alantolactone: A Natural Plant Extract as a Potential Therapeutic Agent for Cancer.Frontiers in pharmacology · 2021Review
- A Novel Bispecific Antibody Targeting PD-L1 and VEGF With Combined Anti-Tumor Activities.Frontiers in immunology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer is the second leading cause of death in the United States (US). The goal of this study was to characterize the trends in cancer incidence and mortality in the US from 1975 to 2016.
methodsIn this study, we analyzed 4,711,958 cancer cases and 21,489,462 cancer death cases from the Surveillance, Epidemiology and End Results (SEER) database. Cancer incidence and mortality were assessed according to sex, race, and age group. Cancer survival rates between 2010 and 2016 were also examined.
resultsThe continuous decline in the overall cancer mortality rate from the early 1990s has resulted in overall decreases of 33.6% and 23.6% in the cancer mortality rates of males and females, respectively. In males, the top three leading cancers and causes of cancer death from 1975 to 2016 were prostate, lung and bronchial, and colon and rectal cancers, while in females, the top three leading cancers and causes of cancer death from 1979 to 2016 were breast, lung and bronchial, and colon and rectal cancers. The 5-year relative survival rates of males and females for all cancers combined, diagnosed from 2010-2016, were 68.5% and 70.1%, respectively. The overall cancer incidence and mortality were higher in males than females from 1975-2016. Also, black people had higher mortality and shorter survival rates for all cancers combined compared with white people (in both sexes).
conclusionsThis study presents a comprehensive overview of cancer incidence and mortality in the US over the past 42 years. Such information can provide a scientific basis for cancer prevention and control.
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