Evidence map›Paper›PMID 33490143›Full record

ReviewAnnals of translational medicine2020

Chinese Expert Consensus on the Nucleic Acid Detection of SARS-CoV-2.

Zijie Liu, Yongqing Tong, Jun Wu, Lutao Du, Chaojun Wei, Wei Cui, Yongtong Cao, Ming Chen, Zhen Cai, Wei Chen and 26 more

Open access · diamondAbstract readReview
In one paragraph

Review in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 1 country.

Zijie LiuYunnan Key Laboratory of Laboratory Medicine, Kunming, China.
Yongqing TongLaboratory Medicine Center, Renmin Hospital of Wuhan University, Wuhan, China.
Jun WuDepartment of Clinical Laboratory, Shanghai General Hospital Jiading Branch, Shanghai, China.
Lutao DuLaboratory Medicine Center of The Second Hospital of Shandong University, Jinan, China.
Chaojun WeiThe Institute of Clinical Research and Translational Medicine, Gansu Provincial Hospital, Lanzhou, China.
Wei CuiDepartment of Laboratory Medicine, Cancer Hospital Chinese Academy of Medical Sciences, Beijing, China.
Yongtong CaoLaboratory Department of China-Japan Friendship Hospital, Beijing, China.
Ming ChenLaboratory Department of Southwest Hospital, Chongqing, China.
Zhen CaiDepartment of Laboratory Medicine, Nanfang Hospital of Southern Medical University, Guangzhou, China.
Wei ChenDepartment of Laboratory Medicine, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Haitao DingDepartment of Laboratory Medicine, People's Hospital of Inner Mongolia Autonomous Region, Hohhot, China.
Ming GuanDepartment of Laboratory Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Wei GuoDepartment of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Chunfang GaoDepartment of Laboratory Medicine, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Xiaoke HaoDepartment of Laboratory Medicine, Xijing Hospital, Air Force Military Medical University, Xi'an, China.
Chengjin HuDepartment of Laboratory Diagnosis, 960th Hospital of Chinese PLA, Jinan, China.
Shan HuangGuizhou Province Center for Clinical Laboratory, Guiyang, China.
Yanfang JiangGene Diagnostic Center of the First Hospital of Jilin University, Changchun, China.
Jinming LiNational Center for Clinical Laboratories, Beijing, China.
Ping LiMedical Laboratory and Pathology Center, the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Changsha, China.
Zhuo LiDepartment of Laboratory Medicine, the First Affiliated Hospital of Xi'an Medical College, Xian, China.
Liang MingDepartment of Laboratory Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shiyang PanDepartment of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zuojun ShenScientific Research Department of the First Affiliated Hospital of University of Science and Technology of China, Hefei, China.
Jianrong SuDepartment of Laboratory Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Ziyong SunDepartment of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hui WangDepartment of Laboratory Medicine, Peking University People's Hospital, Beijing, China.
Junjun WangDepartment of Laboratory Medicine, Eastern Theater General Hospital; Nanjing, China.
Bin XuProvincial Clinical Inspection Center of Jiangsu Cancer Hospital, Nanjing, China.
Nong YuLaboratory of Suzhou Branch of Xinhua Hospital Affiliated to Shanghai Jiaotong University, Suzhou, China.
Lei ZhengDepartment of Laboratory Medicine, Nanfang Hospital of Southern Medical University, Guangzhou, China.
Yi ZhangDepartment of Laboratory Medicine, Qilu Hospital of Shandong University, Jinan, China.
Xin ZhangDepartment of Laboratory Medicine of Xinjiang Production and Construction Corps Hospital, Urumqi, China.
Ying ZhangDepartment of Clinical Laboratory Medicine, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yong DuanYunnan Key Laboratory of Laboratory Medicine, Kunming, China.
Chengbin WangDepartment of Clinical Laboratory Medicine, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Kunming Medical University · CNFirst Affiliated Hospital of Kunming Medical University · CNSecond Hospital of Shandong University · CNShanghai First People's Hospital · CNSouthwest Hospital · CNWuhan University · CNChina-Japan Friendship Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNGansu Provincial Hospital · CNChinese PLA General Hospital · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNFirst Affiliated Hospital of Zhengzhou University · CNHuashan Hospital · CNHuazhong University of Science and Technology · CNJiading District Central Hospital · CNNanfang Hospital · CNPeking University · CNRenmin Hospital of Wuhan University · CNSouthern Medical University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) has already become a pandemic wherein the infection's timely diagnosis has proven beneficial to patient treatment and disease control. Nucleic acid detection has been the primary laboratory diagnostic method for the detection of SARS-CoV-2. To ensure laboratory staff safety and quality nucleic acid testing, the Chinese Society of Laboratory Medicine formulated this consensus, based on the Chinese National Recommendations and previous literature for nucleic acid detection. A working group comprises 34 hospital professionals experience with real-time polymerase chain reactions (PCR) testing for SARS-CoV-2 drafted guidance statements during online discussions. A modified Delphi methodology was used in forming a consensus among a wider group of hospital professionals with SARS-CoV-2 detection experience. Guidance statements were developed for four categories: (I) specimen type, priority, collecting, transportation and receiving; (II) nucleic acid isolation and amplification; (III) quality control; (IV) biosafety management and decontamination. The modified Delphi voting process included a total of 29 guidance statements and final agreement. Consensus was reached after two rounds of voting. Recommendations were established for the detection of SARS-CoV-2 using real time PCR testing based on evidence and group consensus. The manuscript was evaluated against The Appraisal of Guidelines for Research & Evaluation Instrument (AGREE II) and was developed to aid medical laboratory staff in the detection of the ribonucleic acid (RNA) of SARS-CoV-2.

Indexed as

coronavirus disease 2019 (COVID-19)nucleic acidpolymerase chain reaction (PCR)SARS-CoV-2

Identifiers

PMID33490143
PMCPMC7812184
OpenAlexW3112668067

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.