Evidence map›Paper›PMID 33490049›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Production of Long Chain Fatty Alcohols Found in Bumblebee Pheromones by

Jaroslav Hambalko, Peter Gajdoš, Jean-Marc Nicaud, Rodrigo Ledesma-Amaro, Michal Tupec, Iva Pichová, Milan Čertík

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Jaroslav HambalkoFaculty of Chemical and Food Technology, Institute of Biotechnology, Slovak University of Technology, Bratislava, Slovakia.
Peter GajdošFaculty of Chemical and Food Technology, Institute of Biotechnology, Slovak University of Technology, Bratislava, Slovakia.
Jean-Marc NicaudFrench National Research Institute for Agriculture (INRAE), Food and Environment, AgroParisTech, Micalis Institute, Université Paris-Saclay, Jouy-en-Josas, France.
Rodrigo Ledesma-AmaroDepartment of Bioengineering and Imperial College Centre for Synthetic Biology, Faculty of Engineering, Imperial College London, London, United Kingdom.
Michal TupecInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czechia.
Iva PichováInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czechia.
Milan ČertíkFaculty of Chemical and Food Technology, Institute of Biotechnology, Slovak University of Technology, Bratislava, Slovakia.
Slovak University of Technology in Bratislava · SKCzech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZImperial College London · GBMicrobiologie de l’alimentation au service de la santé · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fatty alcohols (FA-OH) are aliphatic unbranched primary alcohols with a chain of four or more carbon atoms. Besides potential industrial applications, fatty alcohols have important biological functions as well. In nature, fatty alcohols are produced as a part of a mixture of pheromones in several insect species, such as moths, termites, bees, wasps, etc. In addition, FA-OHs have a potential for agricultural applications, for example, they may be used as a suitable substitute for commercial insecticides. The insecticides have several drawbacks associated with their preparation, and they exert a negative impact on the environment. Currently, pheromone components are prepared mainly through the catalytic hydrogenation of plant oils and petrochemicals, which is an unsustainable, ecologically unfriendly, and highly expensive process. The biotechnological production of the pheromone components using engineered microbial strains and through the expression of the enzymes participating in the biosynthesis of these components is a promising approach that ensures ecological sustenance as well. The present study was aimed at evaluating the production of FA-OHs in the oleaginous yeast,

Indexed as

Bombusfatty alcoholmetabolic engineeringpheromonereductaseYarrowia lipolytica

Identifiers

PMID33490049
PMCPMC7820814
OpenAlexW3118910711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.