Evidence map›Paper›PMID 33489945›Full record

ArticleGerms2020

Reliability of phenotypic methods for detection of colistin resistance among carbapenem-resistant

Nevine S Fam, Sara H Mohamed, Doaa Gamal, Reham M Wasfy, May S Soliman, Amani A El-Kholy

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Article in Germs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2023
    Review
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nevine S FamMD, Department of Microbiology, Theodor Bilharz Research Institute, PM Box 30 Imbaba, Giza, Egypt.
Sara H MohamedPhD, Department of Microbiology, National Organization for Drug Control and Research, Giza, Egypt.
Doaa GamalMD, Department of Microbiology, Theodor Bilharz Research Institute, PM Box 30 Imbaba, Giza, Egypt.
Reham M WasfyMSc, Department of Microbiology, Theodor Bilharz Research Institute, PM Box 30 Imbaba, Giza, Egypt.
May S SolimanMD, Department of Clinical Pathology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Amani A El-KholyMD, Department of Clinical Pathology, Faculty of Medicine, Cairo University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction

methodsA total of 22 carbapenem-resistant

resultsPhenotypic testing showed that nine of 22 isolates (40.9%) were colistin-resistant by BMD and seven of them were also resistant by AD, with the categorical agreement (CA) of 72.7% and essential agreement (EA) of 90.9%. Colistin MIC results ranged from 1-8 µg/mL and 1-32 µg/mL by both AD and BMD respectively. Detection of colistin resistance by gradient test and automated system showed high very major error (VME) rates (40.9%) compared to BMD with a lack of CA between them. AD gave moderate agreement with BMD by 90.9% EA, 72.7% CA and only 9.1% VME.

conclusionsIn delineating colistin breakpoints BMD followed by AD method are defined as the only reliable phenotypic methods for colistin resistance evaluation. More rapid and reliable tests, other than BMD and AD, are required for the convenient detection of colistin resistance in the routine clinical microbiology laboratory daily workflow.

Indexed as

Acinetobacter baumanniiautomated system (VITEK-2)broth microdilutionColistingradient test

Identifiers

PMID33489945
PMCPMC7811857

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