Evidence map›Paper›PMID 33489923›Full record

ArticleFrontiers in oncology2020

TSPAN7 Exerts Anti-Tumor Effects in Bladder Cancer Through the PTEN/PI3K/AKT Pathway.

Xi Yu, Shenglan Li, Mingrui Pang, Yang Du, Tao Xu, Tao Bai, Kang Yang, Juncheng Hu, Shaoming Zhu, Lei Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Genes · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xi YuDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Shenglan LiDepartment of Radiography, Renmin Hospital of Wuhan University, Wuhan, China.
Mingrui PangDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Yang DuDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Tao XuDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Tao BaiDepartment of Urology, Wuhan No. 1 Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Kang YangDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Juncheng HuDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Shaoming ZhuDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Lei WangDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Xiuheng LiuDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Renmin Hospital of Wuhan University · CNWuhan University · CNWuhan No.1 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tetraspanin protein superfamily participate in the dynamic regulation of cellular membrane compartments expressed in a variety of tumor types, which may alter the biological properties of cancer cells such as cell development, activation, growth and motility. The role of tetraspanin 7 (TSPAN7) has never been investigated in bladder cancer (BCa). In this study, we aimed to investigate the biological function of TSPAN7 and its therapeutic potential in human BCa. First,

Indexed as

apoptosisbladder cancercell cyclePI3K/AKTPTENTSPAN7

Identifiers

PMID33489923
PMCPMC7821430
OpenAlexW3119334495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.