ArticleFrontiers in oncology2020
Whole-Lesion Histogram Analysis of the Apparent Diffusion Coefficient as a Quantitative Imaging Biomarker for Assessing the Level of Tumor-Infiltrating Lymphocytes: Value in Molecular Subtypes of Breast Cancer.
Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diffusion-Weighted MRI for the Assessment of Molecular Prognostic Biomarkers in Breast Cancer.Korean journal of radiology · 2024Pooled it
- Evaluating the predictive value of dynamic contrast-enhanced MRI and six diffusion models for prognostic factors in mass-type invasive ductal carcinoma of the breast.BMC medical imaging · 2026Article
- Breast cancer pharmacotherapy and imaging interpretation: pathophysiological perspectives and clinical application.Japanese journal of radiology · 2026Review
- Comparative analysis of multi-zone peritumoral radiomics in breast cancer for predicting NAC response using ABVS-based deep learning models.Frontiers in oncology · 2025Article
- Relationship between kinetic parameters of ultrafast dynamic contrast-enhanced (DCE) MRI and tumor-infiltrating lymphocytes (TILs) in breast cancer.Japanese journal of radiology · 2025Article
- Apparent diffusion coefficient and tissue stiffness are associated with different tumor microenvironment features of hepatocellular carcinoma.European radiology · 2024Article
- Article
- Identification of triple-negative breast cancer and androgen receptor expression based on histogram and texture analysis of dynamic contrast-enhanced MRI.BMC medical imaging · 2023Article
- Tumor infiltrating lymphocytes and radiological picture of the tumor.Medical oncology (Northwood, London, England) · 2023Review
- Article
- The value of whole-lesion histogram analysis based on field‑of‑view optimized and constrained undistorted single shot (FOCUS) DWI for predicting axillary lymph node status in early-stage breast cancer.BMC medical imaging · 2022Article
- Whole lesion histogram analysis of apparent diffusion coefficient predicts therapy response in locally advanced rectal cancer.World journal of gastroenterology · 2022Article
- Performance of radiomics models for tumour-infiltrating lymphocyte (TIL) prediction in breast cancer: the role of the dynamic contrast-enhanced (DCE) MRI phase.European radiology · 2022Article
- Nomogram for the prediction of triple-negative breast cancer histological heterogeneity based on multiparameter MRI features: A preliminary study including metaplastic carcinoma and non- metaplastic carcinoma.Frontiers in oncology · 2022Article
- Stromal tumor-infiltrating lymphocytes level as a prognostic factor for resected intrahepatic cholangiocarcinoma and its prediction by apparent diffusion coefficient.International journal of clinical oncology · 2021Article
- Article
- Radiomics Assessment of the Tumor Immune Microenvironment to Predict Outcomes in Breast Cancer.Frontiers in immunology · 2021Article
- Whole Volume Apparent Diffusion Coefficient (ADC) Histogram as a Quantitative Imaging Biomarker to Differentiate Breast Lesions: Correlation with the Ki-67 Proliferation Index.BioMed research international · 2021Article
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11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess whether apparent diffusion coefficient (ADC) metrics can be used to assess tumor-infiltrating lymphocyte (TIL) levels in breast cancer, particularly in the molecular subtypes of breast cancer.
methodsIn total, 114 patients with breast cancer met the inclusion criteria (mean age: 52 years; range: 29-85 years) and underwent multi-parametric breast magnetic resonance imaging (MRI). The patients were imaged by diffusion-weighted (DW)-MRI (1.5 T) using a single-shot spin-echo echo-planar imaging sequence. Two readers independently drew a region of interest (ROI) on the ADC maps of the whole tumor. The mean ADC and histogram parameters (10
resultsA statistically significant difference existed in the 10
conclusionsOur findings suggest that whole-lesion ADC histogram parameters can be used as surrogate biomarkers to evaluate TIL levels in molecular subtypes of breast cancer.
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