Evidence map›Paper›PMID 33489777›Full record

ArticleToxicology reports2021

Hepatoprotective, antioxidant and, anti-inflammatory potentials of gallic acid in carbon tetrachloride-induced hepatic damage in Wistar rats.

S I Ojeaburu, K Oriakhi

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Review
  5. Role of gallic acid in sarcopenia in D-galactose-treated mice.Iranian journal of basic medical sciences · 2026
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  18. Delayed treatment with hydro-ethanolic extract ofPharmaceutical science advances · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

S I OjeaburuDepartment of Biochemistry, Faculty of Life Sciences, University of Benin, Benin City, Nigeria.
K OriakhiDepartment of Medical Biochemistry, School of Basic Medical Sciences, University of Benin, Benin City, Nigeria.
University of Benin · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gallic acid (GA) is a known phenolic compound with anti-inflammatory, antioxidant, and anti-cancer activities. The objective of this research is to evaluate the preventive role of GA against carbon tetrachloride (CCl

Indexed as

ALB, albuminALP, alkaline phosphataseALT, alanine transaminaseAnti-inflammatoryAntioxidantARE, antioxidant response elementAST, aspartate transaminaseCAT, catalaseCCl4, carbon tetrachloridecDNA, complementary deoxyribonucleic acidCOX2, cyclooxygenase 2CytokinesDGA, dodecylgallateGA, gallic acidGallic acidGAPDH, glyceraldehydes3-phosphate dehydrogenaseGGT, gamma-glutamyl transpeptidaseGSH, glutathioneIL-1β, interleukin 1betaIL-6, interleukin 6iNOS, inducible nitric oxide synthaseKeap1, kelch-like ECH-associated protein 1Liver diseaseMDA, maloniadehydeNF-κB, nuclear factor kappa light chain enhancer of activated B cellsNrf 2, nuclear factor erythroid- derived 2 like 2 genesPBS, phosphate-buffered salineqPCR, quantitative polymerase chain reactionRNA, ribonucleic acidRT-PCR, reverse transcription-polymerase chain reactionSOD, superoxide dismutaseSYBR, green fluorescent DNA StainTB, total bilirubinTNF α, tumor necrosis factor-alphaTP, total protein

Identifiers

PMID33489777
PMCPMC7806503
OpenAlexW3119027505

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.