Evidence map›Paper›PMID 33489693›Full record

ArticleInternational cancer conference journal2021

Germline multigene panel testing revealed a

Tomoko Yoshihama, Akira Hirasawa, Kokichi Sugano, Teruhiko Yoshida, Mineko Ushiama, Arisa Ueki, Tomoko Akahane, Yoshiko Nanki, Kensuke Sakai, Takeshi Makabe and 5 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International cancer conference journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Germline Whole-Gene Deletion of FH Diagnosed from Tumor Profiling.International journal of molecular sciences · 2021
    Article
  4. Pitfall in the diagnosis of Lynch syndrome.International cancer conference journal · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tomoko YoshihamaDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Akira HirasawaDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0003-4124-5488
Kokichi SuganoCenter for Medical Genetics, Keio University School of Medicine, Tokyo, Japan.
Teruhiko YoshidaDepartment of Genetic Medicine and Services, National Cancer Center Hospital, Tokyo, Japan.
Mineko UshiamaDepartment of Genetic Medicine and Services, National Cancer Center Hospital, Tokyo, Japan.
Arisa UekiCenter for Medical Genetics, Keio University School of Medicine, Tokyo, Japan.
Tomoko AkahaneDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Yoshiko NankiDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Kensuke SakaiDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Takeshi MakabeDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Wataru YamagamiDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Nobuyuki SusumuDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Kaori KameyamaDepartment of Pathology, Showa University Northern Yokohama Hospital, Kanagawa, Japan.
Kenjiro KosakiCenter for Medical Genetics, Keio University School of Medicine, Tokyo, Japan.
Daisuke AokiDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There has been a rapid advance in germline multigene panel testing by next-generation sequencing, and it is being widely used in clinical settings. A 56-year-old woman suspected of having Lynch syndrome was identified as a

Indexed as

BRCA2Genetic counselingHereditary breast and ovarian cancerLynch syndromeMultigene panel testing

Identifiers

PMID33489693
PMCPMC7797406

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.