Evidence map›Paper›PMID 33489448›Full record

ArticleAmerican journal of blood research2020

Zamzam water is pathogen-free, uricosuric, hypolipidemic and exerts tissue-protective effects: relieving BBC concerns.

Hany Salah Mahmoud, Rehab A Eltahlawi, Abdulhalem Abdulsamad Jan, Osama Alhadramy, Tamer M Soliman, Sayed Mostafa El Sayed, Hesham I Abdallah, Momen El-Shazley, Noha M Shafik, Reham A Mariah and 10 more

Open access · greenAbstract read
In one paragraph

Article in American journal of blood research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 2 countries.

Hany Salah MahmoudProphetic Medicine Course and Research, Taibah College of Medicine, Taibah University Al-Madinah Al-Munawwarah, Saudi Arabia.
Rehab A EltahlawiDepartment of Microbiology and Immunology, Faculty of Medicine, Zagazig University Zagazig, Egypt.
Abdulhalem Abdulsamad JanLaboratory and Blood Bank General Director, King Fahad Hospital Al-Madinah Al-Munawwarah, Saudi Arabia.
Osama AlhadramyDivision of Cardiology, Department of Medicine, Taibah College of Medicine, Taibah University Al-Madinah Al-Munawwarah, Saudi Arabia.
Tamer M SolimanDepartment of Clinical Pathology, Sohag Faculty of Medicine, Sohag University Egypt.
Sayed Mostafa El SayedAnatomy and Embryology Department, Faculty of Medicine, Taibah University Saudi Arabia.
Hesham I AbdallahAnatomy and Embryology Department, Faculty of Medicine, Taibah University Saudi Arabia.
Momen El-ShazleyDepartment of Medicine, Taibah College of Medicine, Taibah University Al-Madinah Al-Munawwarah, Saudi Arabia.
Noha M ShafikDepartment of Biochemistry, Tanta Faculty of Medicine, Tanta University Egypt.
Reham A MariahDepartment of Biochemistry, Tanta Faculty of Medicine, Tanta University Egypt.
Noha El-DabieDepartment of Pathology, Faculty of Medicine, Sohag University Egypt.
Mohamed Abdel-HaleemDepartment of Ear, Nose and Throat, College of Medicine, Taibah University Saudi Arabia.
Shaima Mohamed Abdelfattah HassanDepartment of Histology and Cell Biology, Faculty of Medicine, Menoufia University Egypt.
Manal Mohamed Helmy NaboDivision of Pediatric Cardiology, Department of Pediatrics, Maternity and Children Hospital Hail, Saudi Arabia.
Hassan El-AlafDepartment of Medical Physiology, Sohag Faculty of Medicine, Sohag University Egypt.
Hussam BaghdadiDepartment of Clinical Biochemistry and Molecular Medicine, Taibah Faculty of Medicine, Taibah University Al-Madinah Al-Munawwarah, Saudi Arabia.
Reda S YousefDepartment of Medical Biochemistry, Sohag Faculty of Medicine, Sohag University Egypt.
Ahmed Alamir MahmoudDepartment of Medical Biochemistry, Sohag Faculty of Medicine, Sohag University Egypt.
Salah Mohamed El SayedProphetic Medicine Course and Research, Taibah College of Medicine, Taibah University Al-Madinah Al-Munawwarah, Saudi Arabia.
Soliman M AmerFamily and Community Medicine Department, Taibah University Al-Medinah, Saudi Arabia.
Taibah University · SASohag University · EGAin Shams University · EGTanta University · EGAl-Azhar University · EGKing Fahad Hospital Jeddah · SAMaternity and Children's Hospital · SAMenoufia University · EGZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zamzam water is the most frequently used drinking water by millions of people in Saudi Arabia. It is carried all the time by millions of pilgrims to their home countries as gifts to close and near relatives and friends. Safety of constituents of Zamzam water is a vital health topic. British Broadcasting Corporation (BBC) raised many health concerns regarding the high serum arsenic and nitrate contents in Zamzam water that may cause cancer. It is role of scientific research to present scientific facts to relieve such concerns. Arsenic is a carcinogen while nitrate causes methemogloinemia that affect oxygen carriage by haemoglobin. An ethical committee approval was obtained. Eighteen white albino mice (40-45 g) were used in this study. Three experimental groups were allocated (six mice per group): tap water group, distilled water group and Zamzam water group. Our data revealed that Zamzam water exerts tissue-protective effects that contradict malignancy. Our data proved that Zamzam water is pathogen-free causing no bacterial growth on CLED agar colonies. Zamzam water consumption for three consecutive months in mice was quite safe for the general health and significantly decreased serum uric acid (

Indexed as

BBC concernshistologykidney functionsliver functionsuric acidZamzam water

Identifiers

PMID33489448
PMCPMC7811908
OpenAlexW3122408149

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.