Evidence map›Paper›PMID 33489442›Full record

ArticleAmerican journal of blood research2020

Clinical utility of procalcitonin in bacterial infections in patients undergoing hematopoietic stem cell transplantation.

Amit Bansal, Preethi Jeyaraman, S K Gupta, Nitin Dayal, Rahul Naithani

Open access · greenAbstract read
In one paragraph

Article in American journal of blood research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amit BansalPharmaceutical Sciences and Research University New Delhi, India.
Preethi JeyaramanDivision of Hematology and Bone Marrow Transplant, Max Super-Speciality Hospital Saket, New Delhi, India.
S K GuptaPharmaceutical Sciences and Research University New Delhi, India.
Nitin DayalDepartment of Lab Medicine, Max Super-Speciality Hospital Saket, New Delhi, India.
Rahul NaithaniDivision of Hematology and Bone Marrow Transplant, Max Super-Speciality Hospital Saket, New Delhi, India.
Max Super Speciality Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfections are major contributor to morbidity and mortality in patients undergoing bone marrow transplant (BMT).

objectiveTo assess role of serum procalcitonin (PCT) as a useful biomarker for the infections and outcomes in these patients.

methodsRetrospective observational study.

resultsTotal 47 patients with febrile episodes were enrolled. Twenty patients underwent autologous BMT and 27 underwent allogeneic BMT. Bacterial infections were documented in 18/47 (38%) patients. Forty patients were neutropenic. The median fever duration was 10 days (range 3-30 days) in positive procalcitonin level group whereas it was 4 days (range 1-18) in negative group. This was statistically significant (P=0.000). Procalcitonin levels were high in 8/9 episodes of sepsis (P=0.029). Intensive care unit transfers and death were significantly higher in PCT positive group as compared to PCT negative group.

conclusionSerum procalcitonin levels provide prognostic information of worse outcome in patients undergoing HSCT.

Indexed as

Bone marrow transplantinfectionprocalcitonin

Identifiers

PMID33489442
PMCPMC7811896
OpenAlexW3125094832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.