ArticleCritical care research and practice2020
The Effect of Fluid Overload on Attributable Morbidity after Cardiac Surgery: A Retrospective Study.
Article in Critical care research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- The association of midregional pro-adrenomedullin (MR-proADM) at ICU admission and fluid overload in patients post elective cardiac surgery.Scientific reports · 2024Trial
- Feasibility and safety of intravenous tolvaptan administration immediately upon ICU admission after cardiac surgery with cardiopulmonary bypass.Surgery today · 2026Article
- Preoperative and intraoperative risk factors for impaired pulmonary oxygenation after cardiopulmonary bypass: a single-center retrospective analysis.Journal of cardiothoracic surgery · 2026Article
- Article
- Ultrafiltration in the critically ill patient: a framework for personalized care.Critical care (London, England) · 2026Review
- Perioperative fluid accumulation and clinical outcomes after cardiac surgery: a systematic review and Bayesian meta-analysis.Journal of anesthesia, analgesia and critical care · 2026Review
- Impact of Acute Kidney Injury on Hospitalization Outcomes in Patients with Chronic Kidney Disease Undergoing Cardiac Procedures with Cardiopulmonary Bypass in the United States.Journal of health economics and outcomes research · 2026Article
- Intraoperative Factors Associated With Mechanical Ventilation Duration Following Aortic Surgery.Journal of cardiothoracic and vascular anesthesia · 2025Observational
- Pilot randomized controlled trial of restricted versus liberal crystalloid fluid management in pediatric post-operative and trauma patients.Pilot and feasibility studies · 2023Article
- Ventilator-associated events: From surveillance to optimizing management.Journal of intensive medicine · 2023Review
- Usefulness of the velocity-time integral of the left ventricular outflow tract variability index to predict fluid responsiveness in patients undergoing cardiac surgery.Echo research and practice · 2023Article
- Study of the accuracy of a radial arterial pressure waveform cardiac output measurement device after cardiac surgery.Journal of cardiothoracic surgery · 2023Observational
- Fluid Overload and Precision Net Ultrafiltration in Critically Ill Patients.Cardiorenal medicine · 2023Review
- Fluid overload and mortality in critically ill patients with severe heart failure and cardiogenic shock-An observational cohort study.Frontiers in medicine · 2022Article
- Intraoperative fluid balance and cardiac surgery-associated acute kidney injury: a multicenter prospective study.Brazilian journal of anesthesiology (Elsevier)Observational
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAlthough the detrimental effects of excessive perioperative fluid administration are generally well established, data in the setting of cardiac surgery remain less robust.
methodsIn this retrospective single-center observational study, the total fluid balance in the first 12 hours during and after surgery was evaluated. Primary endpoint was the relationship between total fluid balance and the incidence of prolonged mechanical ventilation. For this purpose, data were divided into quartiles (Q); prolonged mechanical ventilation and prolonged length of stay (LOS) in the ICU were defined as Q4. Secondary endpoints were prolonged LOS in the ICU, incidence of acute kidney injury (AKI; defined as a 1.5-fold increase in serum creatinine during, relative to baseline), and ICU mortality.
resultsIn a 3-year period, 748 patients were included. In a univariate analysis, the median duration of mechanical ventilation was 2.9 h [2.4-3.7] in Q1 of the fluid balance and increased significantly to 4.7 h [3.1-9.2] in Q4 of the fluid balance (
conclusionsPerioperative fluid administration in cardiac surgery patients was independently associated with prolonged mechanical ventilation and prolonged LOS in the ICU.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.