Evidence map›Paper›PMID 33489349›Full record

ArticleJournal of ophthalmology2020

Factors Associated with the Clinical Course of Vitreomacular Traction.

Petros Petrou, Evangelia Chalkiadaki, Marie-Helene Errera, Sidath Liyanage, Louisa Wickham, Evangelia Papakonstantinou, Aristotelis Karamaounas, Menelaos Kanakis, Ilias Georgalas, Stylianos Kandarakis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
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  3. Vitreomacular traction - a review.Eye (London, England) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Petros PetrouFirst Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID https://orcid.org/0000-0002-7358-1251
Evangelia ChalkiadakiFirst Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Marie-Helene ErreraUniversity of Pittsburg, Pittsburgh, PA, USA.
Sidath LiyanageBristol Eye Hospital, Bristol, UK.
Louisa WickhamMoorfields Eye Hospital, London, UK.
Evangelia PapakonstantinouFirst Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Aristotelis KaramaounasFirst Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Menelaos KanakisFirst Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Ilias GeorgalasFirst Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Stylianos KandarakisFirst Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.
David CharterisMoorfields Eye Hospital, London, UK.
National and Kapodistrian University of Athens · GRMoorfields Eye Hospital · GBBristol Eye Hospital · GBPittsburg State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo analyze the optical coherence tomography (OCT) characteristics as well as the clinical and demographic features to investigate their possible role to the course of vitreomacular traction syndrome.

methodsThe inclusion criteria were vitreomacular adhesion with traction causing distortion of the retinal architecture, with or without the presence of an epiretinal membrane, regardless of the size of the adhesion; age >18 years; follow-up of at least three months; and adequate quality OCT scan. Measurements of foveal thickness, average macular thickness, macular volume, maximum vertical and horizontal vitreomacular adhesion, nasal and temporal angles of traction, hyaloid hyperreflectivity, the presence of an epiretinal membrane (ERM), and cone outer segment tips detachment were obtained.

results150 eyes were included in the analysis. 36 eyes (24%) developed complete resolution at the last visit, 19 eyes (12.7%) formed a full-thickness macular hole, and 95 eyes (63.3%) showed no resolution of the traction. Better BCVA at the first visit was associated with an increased likelihood of resolution of the VMT, but increasing age, CMT, and BCVA in the end of the follow-up was associated with a reduction in the likelihood of resolving. Of the other variables that were studied, no statistical significant predictors were identified.

conclusionsBetter BCVA in the first visit was associated with an increased likelihood of resolution of the VMT that occurred in 24% of our cases. Other factors such as the vertical area of adhesion and the angle of adhesion were not identified as prognostic factors affecting the clinical course of the disease.

Identifiers

PMID33489349
PMCPMC7803219
OpenAlexW3114404930

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.