Evidence map›Paper›PMID 33489344›Full record

ArticleJournal of ophthalmology2020

Retinal Structural and Microvascular Alterations in Different Acute Ischemic Stroke Subtypes.

Ying Zhang, Ce Shi, Yihong Chen, Weicheng Wang, Shenghai Huang, Zhao Han, Xianda Lin, Fan Lu, Meixiao Shen

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  9. Alzheimer's disease pathophysiology in the Retina.Progress in retinal and eye research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ying ZhangSchool of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China.
Ce ShiSchool of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China.
Yihong ChenSchool of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China.
Weicheng WangSchool of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China.
Shenghai HuangSchool of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China.
Zhao HanThe Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang, China.
Xianda LinThe Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang, China.
Fan LuSchool of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China.ORCID https://orcid.org/0000-0003-0846-147X
Meixiao ShenSchool of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-4297-962X
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRetinal structural and microvascular damages reflect damage to cerebral microvasculature and neurons. We aimed to investigate neovascular unit abnormalities among patients with large-artery atherosclerosis (LAA) or small-vessel occlusion (SAA) and control subjects.

methodsTwenty-eight LAA patients, forty-one SAA patients, and sixty-five age- and gender-matched controls were recruited. Based on optical coherence tomography angiography (OCTA), retinal capillary vessel density was assessed in the general and local sectors, and the thickness of individual retinal layer was extracted from retinal structural images. The differences between structural and microvascular were analyzed.

resultsThe superior peripapillary retinal nerve fiber layer (pRNFL) thickness was significantly different among the three groups, and the LAA group had the thinnest thickness. Compared to the control group, the deep retinal capillary vessel density in other two stroke subgroups were significantly reduced in all regions except in the inferior region (

Identifiers

PMID33489344
PMCPMC7803129
OpenAlexW3111925767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.