Evidence map›Paper›PMID 33489197›Full record

ArticleClinical case reports2021

Thrombocytosis with acquired von Willebrand disease in an adolescent with sickle cell disease.

Marianne E M Yee, Glaivy Batsuli, Satheesh Chonat, Sunita Park

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06601894 (The Relationship of Platelet Counts With Sickle Cell Anemia in the Eastern Region of Saudi Arabia), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06601894 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

The Relationship of Platelet Counts With Sickle Cell Anemia in the Eastern Region of Saudi Arabia

Typeobservational_patient_registrySponsorMajmaah UniversityRan2024 to 2025Enrolled650ConditionsSickle Cell Anaemia, SCDArmsPlatelets count
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marianne E M YeeAflac Cancer and Blood Disorders Center Children's Healthcare of Atlanta Atlanta GA USA.ORCID https://orcid.org/0000-0001-6082-8385
Glaivy BatsuliAflac Cancer and Blood Disorders Center Children's Healthcare of Atlanta Atlanta GA USA.
Satheesh ChonatAflac Cancer and Blood Disorders Center Children's Healthcare of Atlanta Atlanta GA USA.ORCID https://orcid.org/0000-0002-5909-0800
Sunita ParkDepartment of Pathology and Laboratory Medicine Children's Healthcare of Atlanta Atlanta GA USA.
Emory University · USChildren's Healthcare of Atlanta · US

Funding

Atlanta Pediatric Scholars ProgramK12HD072245 · NICHD · EMORY UNIVERSITY · PI Shari Barkin · 2012 to 2026
$5.5M
Utilizing Dendritic Cell Biology to Characterize the Innate Immune Response to Blood Coagulation ProteinsK99HL150595 · NHLBI · STANFORD UNIVERSITY · PI BATSULI, GLAIVY · 2020 to 2024
$1.0M
NHLBI NIH HHS K99 HL150595NICHD NIH HHS K12 HD072245
6 · The paper itself

Abstract

Thrombocytosis is common in sickle cell disease and may contribute to vaso-occlusion. Hydroxyurea treats extreme thrombocytosis. Acquired von Willebrand disease should be considered prior to aspirin therapy.

Indexed as

acquired Von Willebrand diseasepriapismsickle cell diseasethrombocytosis

Identifiers

PMID33489197
PMCPMC7813102
OpenAlexW3109279629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.