Evidence map›Paper›PMID 33489133›Full record

ArticleClinical case reports2021

New-generation anticancer drugs and medication-related osteonecrosis of the jaw (MRONJ): Late onset 3 years after ipilimumab endovenous administration with a possible role of target therapy.

Agostino Guida, Francesco Perri, Franco Ionna, Paolo A Ascierto, Antonio M Grimaldi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. The Immune Checkpoint Inhibitors Journey: From Early Promise to Lasting Impact.Journal of immunotherapy and precision oncology · 2026
    Review
  2. Review
  3. Bridging the gap - Establishing a dental-oncology service in a cancer centre.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  4. Review
  5. Review
  6. Review
  7. Article
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  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Agostino GuidaMaxillo-facial and ENT Surgery Unit INT - IRCCS "Fondazione G. Pascale" Naples Italy.ORCID https://orcid.org/0000-0003-0177-1301
Francesco PerriHead & Neck/Thyroid Medical Oncology Unit INT - IRCCS "Fondazione G. Pascale" Naples Italy.ORCID https://orcid.org/0000-0001-8158-7509
Franco IonnaMaxillo-facial and ENT Surgery Unit INT - IRCCS "Fondazione G. Pascale" Naples Italy.
Paolo A AsciertoMelanoma, Oncological Immunotherapy and Innovative Therapies Department INT - IRCCS "Fondazione G. Pascale" Naples Italy.
Antonio M GrimaldiMelanoma, Oncological Immunotherapy and Innovative Therapies Department INT - IRCCS "Fondazione G. Pascale" Naples Italy.
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Association of immunotherapy and/or chemotherapy and/or targeted therapy, in sequence or as single therapies, may induce osteonecrosis of the jaw. Multidisciplinary team management of these patients should be provided.

Indexed as

bisphosphonate‐associated osteonecrosisipilimumabmedically compromised patientsmedication‐related osteonecrosis of the jawtarget therapy

Identifiers

PMID33489133
PMCPMC7813008
OpenAlexW3108559591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.