Evidence map›Paper›PMID 33488947›Full record

ArticleOxidative medicine and cellular longevity2021

Apolipoprotein E Polymorphism and Oxidative Stress in Human Peripheral Blood Cells: Can Physical Activity Reactivate the Proteasome System through Epigenetic Mechanisms?

Rebecca Piccarducci, Simona Daniele, Beatrice Polini, Sara Carpi, Lucia Chico, Jonathan Fusi, Filippo Baldacci, Gabriele Siciliano, Ubaldo Bonuccelli, Paola Nieri and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Rebecca PiccarducciDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID https://orcid.org/0000-0001-9577-6650
Simona DanieleDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID https://orcid.org/0000-0001-7391-3087
Beatrice PoliniDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID https://orcid.org/0000-0002-2664-6091
Sara CarpiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID https://orcid.org/0000-0002-3291-9009
Lucia ChicoDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy.ORCID https://orcid.org/0000-0001-5832-7098
Jonathan FusiDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy.ORCID https://orcid.org/0000-0002-7905-6423
Filippo BaldacciDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy.ORCID https://orcid.org/0000-0002-8752-0556
Gabriele SicilianoDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy.
Ubaldo BonuccelliDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy.
Paola NieriDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID https://orcid.org/0000-0001-5809-2938
Claudia MartiniDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID https://orcid.org/0000-0001-9379-3027
Ferdinando FranzoniDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy.ORCID https://orcid.org/0000-0003-2132-8788
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is characterized by proteasome activity impairment, oxidative stress, and epigenetic changes, resulting in

Indexed as

Epigenesis, GeneticExerciseOxidative StressPolymorphism, GeneticAdultAmyloid beta-PeptidesAntioxidantsApolipoproteins EBiomarkersFemaleHumansLeukocytes, MononuclearMaleMicroRNAsProteasome Endopeptidase ComplexRecovery of FunctionAmyloid beta-PeptidesAntioxidantsApoE protein, humanApolipoproteins EBiomarkersMicroRNAsProteasome Endopeptidase Complex

Identifiers

PMID33488947
PMCPMC7796851
OpenAlexW3119764981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.