Evidence map›Paper›PMID 33488939›Full record

ArticleOxidative medicine and cellular longevity2020

Hydrogen Sulfide Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Apoptosis and Affects Autophagy.

Liming Hu, Jia Guo, Li Zhou, Sen Zhu, Chunming Wang, Jiawei Liu, Shanshan Hu, Mulin Yang, Changjun Lin

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Protective effect of HMolecular medicine reports · 2022
    Article
  11. Article
  12. TRAP1 in Oxidative Stress and Neurodegeneration.Antioxidants (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Liming HuSchool of Life Sciences, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0002-6378-4901
Jia GuoSchool of Life Sciences, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0002-6694-0754
Li ZhouSchool of Life Sciences, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0002-4493-0483
Sen ZhuSchool of Life Sciences, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0002-0552-8985
Chunming WangSchool of Life Sciences, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0002-2810-9820
Jiawei LiuSchool of Life Sciences, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0003-1811-0067
Shanshan HuSchool of Life Sciences, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0003-1260-0583
Mulin YangSchool of Life Sciences, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0001-9951-0411
Changjun LinSchool of Life Sciences, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0002-9134-548X
Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related macular degeneration (AMD) is a major cause of visual impairment and blindness among the elderly. AMD is characterized by retinal pigment epithelial (RPE) cell dysfunction. However, the pathogenesis of AMD is still unclear, and there is currently no effective treatment. Accumulated evidence indicates that oxidative stress and autophagy play a crucial role in the development of AMD. H

Indexed as

ApoptosisAutophagyOxidative StressAir PollutantsCell SurvivalHumansHydrogen SulfideProtective AgentsReactive Oxygen SpeciesRetinal Pigment EpitheliumAir PollutantsHydrogen SulfideProtective AgentsReactive Oxygen Species

Identifiers

PMID33488939
PMCPMC7790554
OpenAlexW3115730186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.